Chemical Property of Smoothened Agonist, HCl
Chemical Property:
- PSA：82.70000
- LogP:8.72030
- Sensitive.:Light Sensitive & Hygroscopic
- Water Solubility.:Soluble in water.
- Purity/Quality:
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98%Min *data from raw suppliers
Smoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
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Uses
Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened). This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo. SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.
