3-(4-Aminophenyl)-7-(diethylamino)-4-methylchromen-2-one

Base Information

Chemical Name:3-(4-Aminophenyl)-7-(diethylamino)-4-methylchromen-2-one
CAS No.:36840-64-9
Molecular Formula:C20H22N2O2
Molecular Weight:322.40100
Hs Code.:
DSSTox Substance ID:DTXSID10349750
Nikkaji Number:J1.714.491J
Wikidata:Q82125192
ChEMBL ID:CHEMBL1455263

Synonyms:MLS000028293;3-(4-aminophenyl)-7-(diethylamino)-4-methylchromen-2-one;36840-64-9;SMR000040363;Oprea1_738293;cid_659315;SCHEMBL8132354;CHEMBL1455263;BDBM43932;DTXSID10349750;HMS2174K22;STK530771;AKOS005463396;CCG-279197;NCGC00018960-01;NCGC00018960-02;NCGC00018960-03;3-(4-aminophenyl)-7-(diethylamino)-4-methyl-coumarin;3-(4-aminophenyl)-7-(diethylamino)-4-methyl-2H-chromen-2-one;3-(4-aminophenyl)-7-(diethylamino)-4-methyl-chromen-2-one;3-(4-aminophenyl)-7-(diethylamino)-4-methyl-1-benzopyran-2-one;3-(4-Aminophenyl)-7-(diethylamino)-4-methyl-2H-1-benzopyran-2-one

Suppliers and Price of 3-(4-Aminophenyl)-7-(diethylamino)-4-methylchromen-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-(4-Aminophenyl)-7-(diethylamino)-4-methylchromen-2-one

Chemical Property:

Boiling Point:543.7±50.0 °C(Predicted)
PSA：59.47000
Density:1.191±0.06 g/cm3(Predicted)
LogP:4.77800
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:322.168127949
Heavy Atom Count:24
Complexity:490

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C1=CC2=C(C=C1)C(=C(C(=O)O2)C3=CC=C(C=C3)N)C

Technology Process of 3-(4-Aminophenyl)-7-(diethylamino)-4-methylchromen-2-one

There total 4 articles about 3-(4-Aminophenyl)-7-(diethylamino)-4-methylchromen-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 36840-65-0
3-(4-acetamidophenyl)-7-diethylamino-4-methyl-2H-chromen-2-one

: 36840-64-9
3-(4-aminophenyl)-7-diethylamino-4-methyl-2H-chromen-2-one

Guidance literature:: With hydrogenchloride; In ethanol; at 80 ℃; for 3h;
DOI:10.1002/1099-0690(200204)2002:7<1149::AID-EJOC1149>3.0.CO;2-H

Reference yield:

: 91-44-1,61968-71-6
7-diethylamino-4-methylcoumarin

: 36840-64-9
3-(4-aminophenyl)-7-diethylamino-4-methyl-2H-chromen-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 30 percent / NaOAc; CuCl₂; NaNO₂ / acetone

2: 93 percent / HCl / ethanol / 3 h / 80 °C

With hydrogenchloride; sodium acetate; copper dichloride; sodium nitrite; In ethanol; acetone; 1: Meerwein reaction;
DOI:10.1002/1099-0690(200204)2002:7<1149::AID-EJOC1149>3.0.CO;2-H

Reference yield:

: 122-80-5
N-acetyl-p-phenylenediamine

: 36840-64-9
3-(4-aminophenyl)-7-diethylamino-4-methyl-2H-chromen-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 30 percent / NaOAc; CuCl₂; NaNO₂ / acetone

2: 93 percent / HCl / ethanol / 3 h / 80 °C

With hydrogenchloride; sodium acetate; copper dichloride; sodium nitrite; In ethanol; acetone; 1: Meerwein reaction;
DOI:10.1002/1099-0690(200204)2002:7<1149::AID-EJOC1149>3.0.CO;2-H