ethyl 1-{4-nitrophenyl}-2-methyl-1H-pyrido[3,2-b]indole-3-carboxylate

Base Information

Chemical Name:ethyl 1-{4-nitrophenyl}-2-methyl-1H-pyrido[3,2-b]indole-3-carboxylate
CAS No.:374697-64-0
Molecular Formula:C₂₁H₁₇N₃O₄
Molecular Weight:375.384
Hs Code.:
Mol file:374697-64-0.mol

Synonyms:1H-2-methyl-1-p-nitrophenyl-3-ethoxycarbonylpyrido[3,2-b]indole;

Suppliers and Price of ethyl 1-{4-nitrophenyl}-2-methyl-1H-pyrido[3,2-b]indole-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of ethyl 1-{4-nitrophenyl}-2-methyl-1H-pyrido[3,2-b]indole-3-carboxylate

Chemical Property:

PSA：89.94000
LogP:5.09520

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ethyl 1-{4-nitrophenyl}-2-methyl-1H-pyrido[3,2-b]indole-3-carboxylate

There total 3 articles about ethyl 1-{4-nitrophenyl}-2-methyl-1H-pyrido[3,2-b]indole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 3-ethoxycarbonyl-2-methyl-1-(p-nitrophenyl)-5H-pyrido[3,2-b]indolinium chloride

: 374697-64-0
1H-3-ethoxycarbonyl-2-methyl-1-(p-nitrophenyl)pyrido[3,2-b]indole

Guidance literature:: With potassium hydroxide;
DOI:10.1023/A:1012743802689

Reference yield: 30.0%

: 141-97-9
ethyl acetoacetate

: 2-diimethyliminomeethyl-3-[N-(4-nitrophenyl)amino]indole chloride

: 374697-64-0
1H-3-ethoxycarbonyl-2-methyl-1-(p-nitrophenyl)pyrido[3,2-b]indole

: 3-ethoxycarbonyl-2-methyl-1-(p-nitrophenyl)-5H-pyrido[3,2-b]indolinium chloride

Guidance literature:: With triethylamine; In isopropyl alcohol; at 20 ℃; for 24h;
DOI:10.1023/A:1012743802689

Reference yield:

: 2-diimethyliminomeethyl-3-[N-(4-nitrophenyl)amino]indole chloride

: 374697-64-0
1H-3-ethoxycarbonyl-2-methyl-1-(p-nitrophenyl)pyrido[3,2-b]indole

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / propan-2-ol / 24 h / 20 °C

2: 53 percent / aq. KOH

With potassium hydroxide; triethylamine; In isopropyl alcohol;
DOI:10.1023/A:1012743802689