4-AMINOBENZOIC ACID SODIUM SALT

Base Information

• Chemical Name: 4-AMINOBENZOIC ACID SODIUM SALT
• CAS No.: 555-06-6
• Molecular Formula: C7H6NNaO2
• Molecular Weight: 159.12
• Hs Code.: 2922491000
• Mol file: 555-06-6.mol

Synonyms:Benzoicacid, 4-amino-, monosodium salt (9CI);Benzoic acid, p-amino-, monosodium salt(8CI);Benzoic acid, p-amino-, sodium salt (4CI);Aminobenzoate sodium;Antergyl;Pabavit;Sodium 4-aminobenzoate;Sodium p-aminobenzoate;p-Aminobenzoic acid sodium salt;p-Anino benzenesulfonic acid sodium salt;

Chemical Property of 4-AMINOBENZOIC ACID SODIUM SALT

Chemical Property:

• Appearance/Colour: Yellow powder
• Vapor Pressure: 3.45E-05mmHg at 25°C
• Melting Point: >300 °C(lit.)
• Boiling Point: 339.9 °C at 760 mmHg
• Flash Point: 159.4 °C
• PSA: 66.15000
• LogP: 0.21350
• Storage Temp.: Store at RT.
• Water Solubility.: Soluble in water (50 mg/ml).

Purity/Quality:

98% ^*data from raw suppliers

Aminobenzoate sodium ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Analgesic. 4-Aminobenzoic acid sodium salt is used as a Pharmaceutical intermediate.

Technology Process of 4-AMINOBENZOIC ACID SODIUM SALT

There total 9 articles about 4-AMINOBENZOIC ACID SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → sodium p-aminobenzoate (555-06-6)

Guidance literature:

With sodium hydroxide; In ethanol; at 69.84 ℃; for 1h;

DOI:10.1039/c0ob00764a

Reference yield: 75.0%

1,1,3,3-Tetramethoxypropan-2-on-(4-ethoxycarbonyl)phenylhydrazon (81494-74-8) → sodium p-aminobenzoate (555-06-6) + 2-Amino-1,1,3,3-tetramethoxypropan (81494-56-6)

Guidance literature:

With sodium hydroxide; hydrogen; nickel; In methanol; at 100 ℃; for 100h; under 91938.4 Torr;

Reference yield:

sodium 4-nitrobenzoate (3847-57-2) → sodium p-aminobenzoate (555-06-6)

Guidance literature:

With sodium tetrahydroborate; In water; at 39.84 ℃;

DOI:10.1016/j.molcata.2015.07.031

upstream raw materials:

p-aminoethylbenzoate

1,1,3,3-Tetramethoxypropan-2-on-(4-ethoxycarbonyl)phenylhydrazon

4-methoxycarbonyl aniline

Mesoxaldialdehyd-2-(4-ethoxycarbonyl)phenylhydrazon

Downstream raw materials:

Sodium; 4-((3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-ylamino)-benzoate

4-amino-benzoic acid 2-(3,4-dimethyl-phenyl)-2-oxo-ethyl ester

silver(I) p-aminebenzoate monohydrate

nitrato-(p-aminobenzoato)lead(II)

Refernces

• 1、 -. "Method for synthesizing (2-((4-aminobenzoyl) oxyl) ethyl)sodium". Paragraph 0010. . Retrieved 2017/04/03.
• 2、 Zaltariov, Mirela-Fernanda,Cazacu, Maria,Vornicu, Nicoleta,Shova, Sergiu,Racles, Carmen,Balan, Mihaela,Turta, Constantin. "A new diamine containing disiloxane moiety and some derived Schiff bases: Synthesis, structural characterisation and antimicrobial activity". . p. 490 - 502. Retrieved 2013/09/12.