4-(4-methoxyphenyl)-8-methyl-7-(1-oxo-1-phenylpropan-2-yl)oxychromen-2-one

Base Information

Chemical Name:4-(4-methoxyphenyl)-8-methyl-7-(1-oxo-1-phenylpropan-2-yl)oxychromen-2-one
CAS No.:376379-16-7
Molecular Formula:C26H22O5
Molecular Weight:414.45000
Hs Code.:
Mol file:376379-16-7.mol

Synonyms:4-(4-Methoxy-phenyl)-8-methyl-7-(1-methyl-2-oxo-2-phenyl-ethoxy)-chromen-2-one;

Suppliers and Price of 4-(4-methoxyphenyl)-8-methyl-7-(1-oxo-1-phenylpropan-2-yl)oxychromen-2-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(4-methoxyphenyl)-8-methyl-7-(1-oxo-1-phenylpropan-2-yl)oxychromen-2-one

Chemical Property:

Melting Point:140 - 141 °C
Boiling Point:611.7±55.0 °C(Predicted)
PSA：65.74000
Density:1.232±0.06 g/cm3(Predicted)
LogP:5.42720

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 4-(4-methoxyphenyl)-8-methyl-7-(1-oxo-1-phenylpropan-2-yl)oxychromen-2-one

There total 3 articles about 4-(4-methoxyphenyl)-8-methyl-7-(1-oxo-1-phenylpropan-2-yl)oxychromen-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 2114-00-3
2-bromo-1-phenyl-1-propanone

: 370583-62-3
7-hydroxy-4-(4-methoxyphenyl)-8-methyl-2H-2-chromenone

: 376379-16-7
4-(4-methoxyphenyl)-8-methyl-7-(1-methyl-2-oxo-2-phenylethoxy)-2H-2-chromenone

Guidance literature:: With potassium carbonate; In acetone; at 50 - 56 ℃;
DOI:10.1023/A:1022626402415

Reference yield:

: 608-25-3
2-methylbenzene-1,3-diol

: 376379-16-7
4-(4-methoxyphenyl)-8-methyl-7-(1-methyl-2-oxo-2-phenylethoxy)-2H-2-chromenone

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / conc. H₂SO₄ / ethanol / 0 - 20 °C

2: 84 percent / K₂CO₃ / acetone / 50 - 56 °C

With sulfuric acid; potassium carbonate; In ethanol; acetone; 1: Pechmann condensation / 2: Williamson reaction;
DOI:10.1023/A:1022626402415

Reference yield:

: 2881-83-6
ethyl 4-methoxybenzoylacetate

: 376379-16-7
4-(4-methoxyphenyl)-8-methyl-7-(1-methyl-2-oxo-2-phenylethoxy)-2H-2-chromenone

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / conc. H₂SO₄ / ethanol / 0 - 20 °C

2: 84 percent / K₂CO₃ / acetone / 50 - 56 °C

With sulfuric acid; potassium carbonate; In ethanol; acetone; 1: Pechmann condensation / 2: Williamson reaction;
DOI:10.1023/A:1022626402415