Benzyl (2-oxopiperidin-3-yl)carbamate

Base Information

Chemical Name:Benzyl (2-oxopiperidin-3-yl)carbamate
CAS No.:38150-56-0
Molecular Formula:C13H16N2O3
Molecular Weight:248.282
Hs Code.:2933790090
DSSTox Substance ID:DTXSID40543744,DTXSID40930998
Mol file:38150-56-0.mol

Synonyms:38150-56-0;Benzyl (2-oxopiperidin-3-yl)carbamate;(2-OXO-PIPERIDIN-3-YL)-CARBAMIC ACID BENZYL ESTER;benzyl N-(2-oxopiperidin-3-yl)carbamate;Benzyl (S)-2-oxopiperidin-3-ylcarbamate;(R)-3-(Cbz-amino)-2-piperidone;MFCD08166408;MFCD09264105;Oprea1_491945;Oprea1_545063;SCHEMBL4077967;DTXSID40543744;DTXSID40930998;KVHNKJHAXXEKFU-UHFFFAOYSA-N;Benzyl(2-oxopiperidin-3-yl)carbamate;3-N-CBZ-AMINOPIPERIDIN-2-ONE;AKOS015855286;3-benzyloxycarbonylaminopiperidin-2-one;AB43572;AT25360;SB48280;SY028756;SY029119;EN300-6496671;(2-oxo-3-piperidinyl)-Carbamic acid benzyl ester;(2-OXO-PIPERIDIN-3-YL)-CARBAMICACIDBENZYLESTER;Benzyl hydrogen (2-hydroxy-3,4,5,6-tetrahydropyridin-3-yl)carbonimidate

Suppliers and Price of Benzyl (2-oxopiperidin-3-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Benzyl(2-oxopiperidin-3-yl)carbamate 95+%
1g
$ 353.00

Chemenu
benzyl(2-oxopiperidin-3-yl)carbamate 95%
1g
$ 333.00

American Custom Chemicals Corporation
(2-OXO-PIPERIDIN-3-YL)-CARBAMIC ACID BENZYL ESTER 95.00%
5MG
$ 504.15

Alichem
Benzyl(2-oxopiperidin-3-yl)carbamate
1g
$ 400.00

Total 8 raw suppliers

Chemical Property of Benzyl (2-oxopiperidin-3-yl)carbamate

Chemical Property:

Melting Point:176.5-177.0℃
PSA：74.41000
LogP:1.67170
Storage Temp.:2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:248.11609238
Heavy Atom Count:18
Complexity:301

Purity/Quality:

98% ^*data from raw suppliers

Benzyl(2-oxopiperidin-3-yl)carbamate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(C(=O)NC1)NC(=O)OCC2=CC=CC=C2

Technology Process of Benzyl (2-oxopiperidin-3-yl)carbamate

There total 4 articles about Benzyl (2-oxopiperidin-3-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

: 6692-89-3,13594-52-0
N^α-benzyloxy-carbonyl-L-citrulline

: 100-01-6,104810-17-5
4-nitro-aniline

: 587-90-6
bis-N,N'-(4-nitrophenyl)urea

: 38150-56-0
3-(benzyloxycarbonylamido)-piperidin-2-one

Guidance literature:: With pyridine; phosphorus trichloride; 1.) -20 deg C, 30 min., 2.) room temp., 30 min., 3.) reflux, 3h;
DOI:10.1016/0040-4020(82)80232-9

Reference yield: 14.0%

: 100-01-6,104810-17-5
4-nitro-aniline

: 83575-38-6
N₁-carbamoyl-3-benzyloxycarbonylamidopiperidin-2-one

: 587-90-6
bis-N,N'-(4-nitrophenyl)urea

: 38150-56-0
3-(benzyloxycarbonylamido)-piperidin-2-one

Guidance literature:: In pyridine; for 3.5h; Heating;
DOI:10.1016/0040-4020(82)80232-9

Reference yield:

: 6692-89-3,13594-52-0
N^α-benzyloxy-carbonyl-L-citrulline

: 38150-56-0
3-(benzyloxycarbonylamido)-piperidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 30 percent / PCl₃, pyridine / 1.) -20 deg C, 30 min., 2.) room temp., 30 min., 3.) room temp., 3 days

2: 13 percent / pyridine / 3.5 h / Heating

With pyridine; phosphorus trichloride; In pyridine;
DOI:10.1016/0040-4020(82)80232-9