6-Bromo-5-chloronicotinic acid

Base Information

• Chemical Name: 6-Bromo-5-chloronicotinic acid
• CAS No.: 38185-54-5
• Molecular Formula: C₆H₃BrClNO₂
• Molecular Weight: 236.452
• Hs Code.: 2933399990
• European Community (EC) Number: 865-605-1
• Mol file: 38185-54-5.mol

Synonyms:6-bromo-5-chloronicotinic acid;38185-54-5;6-bromo-5-chloropyridine-3-carboxylic acid;6-bromo-5-chloronicotinicacid;3-Pyridinecarboxylic acid, 6-bromo-5-chloro-;SCHEMBL487373;3-PYRIDINECARBOXYLIC ACID,6-BROMO-5-CHLORO-;6-bromo-5-chloro nicotinic acid;AKOS015891858;AT10807;2-Bromo-3-chloro-5-pyridinecarboxylic acid;A6479;FT-0701272;EN300-155406;Z1269230032

Chemical Property of 6-Bromo-5-chloronicotinic acid

Chemical Property:

• Vapor Pressure: 8.56E-06mmHg at 25°C
• Boiling Point: 359.5oC at 760 mmHg
• Flash Point: 171.2oC
• PSA: 50.19000
• Density: 1.917g/cm3
• LogP: 2.19570
• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 234.90357
• Heavy Atom Count: 11
• Complexity: 167

Purity/Quality:

99%min ^*data from raw suppliers

3-PYRIDINECARBOXYLICACID,6-BROMO-5-CHLORO- 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=C(C=NC(=C1Cl)Br)C(=O)O

Technology Process of 6-Bromo-5-chloronicotinic acid

There total 1 articles about 6-Bromo-5-chloronicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 6-bromo-5-chloro-nicotinic acid (38185-54-5)

Guidance literature:

3-Picolinderivat VII; Oxidation;

DOI:10.1016/S1352-2310(00)00235-1

Reference yield: 73.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + 6-bromo-5-chloro-nicotinic acid (38185-54-5) → 6-Bromo-5-chloro-nicotinic acid methyl ester (78686-80-3)

Guidance literature:

In diethyl ether; Ambient temperature;

DOI:10.1021/je00025a033

Downstream raw materials:

6-Bromo-5-chloro-nicotinic acid methyl ester