(2S)-3-Amino-2-methyl-N,N-bis[(1R)-1-phenylethyl]propanamide

Base Information

Chemical Name:(2S)-3-Amino-2-methyl-N,N-bis[(1R)-1-phenylethyl]propanamide
CAS No.:382180-28-1
Molecular Formula:C20H26N2O
Molecular Weight:310.439
Hs Code.:
DSSTox Substance ID:DTXSID701186460
Mol file:382180-28-1.mol

Synonyms:DTXSID701186460;382180-28-1;(2S)-3-Amino-2-methyl-N,N-bis[(1R)-1-phenylethyl]propanamide

Suppliers and Price of (2S)-3-Amino-2-methyl-N,N-bis[(1R)-1-phenylethyl]propanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (2S)-3-Amino-2-methyl-N,N-bis[(1R)-1-phenylethyl]propanamide

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:310.204513457
Heavy Atom Count:23
Complexity:335

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(CN)C(=O)N(C(C)C1=CC=CC=C1)C(C)C2=CC=CC=C2
Isomeric SMILES:C[C@@H](CN)C(=O)N([C@H](C)C1=CC=CC=C1)[C@H](C)C2=CC=CC=C2

Technology Process of (2S)-3-Amino-2-methyl-N,N-bis[(1R)-1-phenylethyl]propanamide

There total 4 articles about (2S)-3-Amino-2-methyl-N,N-bis[(1R)-1-phenylethyl]propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 537041-91-1
(2S)-N,N-bis[(1R)-1-phenylethyl]-2-methyl-3-{[(1S)-1-phenylethyl]amino}propanamide

: 382180-28-1
3-amino-2-methyl-N,N-bis-(1-phenyl-ethyl)-propionamide

Guidance literature:: With hydrogen; acetic acid; palladium dihydroxide; In ethanol; at 65 ℃; for 12h; under 25080 Torr;
DOI:10.1002/hlca.200290004

Reference yield:

: 10024-74-5,21003-56-5,21003-57-6,23294-41-9,42287-48-9,56210-72-1
(R,R)-N,N-bis-(1-phenylethyl)amine

: 382180-28-1
3-amino-2-methyl-N,N-bis-(1-phenyl-ethyl)-propionamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: 93 percent / Et₃N / CH₂Cl₂

2.1: 98 percent / ethanol / 36 h / Heating

3.1: LHMDS / tetrahydrofuran / 1 h / -78 °C

3.2: HMPA / tetrahydrofuran / -78 °C

4.1: 100 percent / H₂; AcOH / Pd(OH)2 / ethanol / 12 h / 65 °C / 25080 Torr

With hydrogen; acetic acid; triethylamine; lithium hexamethyldisilazane; palladium dihydroxide; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1002/hlca.200290004

Reference yield:

: 364782-99-0
N,N-bis[(1R)-1-phenylethyl]prop-2-enamide

: 382180-28-1
3-amino-2-methyl-N,N-bis-(1-phenyl-ethyl)-propionamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: 98 percent / ethanol / 36 h / Heating

2.1: LHMDS / tetrahydrofuran / 1 h / -78 °C

2.2: HMPA / tetrahydrofuran / -78 °C

3.1: 100 percent / H₂; AcOH / Pd(OH)2 / ethanol / 12 h / 65 °C / 25080 Torr

With hydrogen; acetic acid; lithium hexamethyldisilazane; palladium dihydroxide; In tetrahydrofuran; ethanol;
DOI:10.1002/hlca.200290004