Azulene-1,3-dicarboxylic acid

Base Information

• Chemical Name: Azulene-1,3-dicarboxylic acid
• CAS No.: 38303-39-8
• Molecular Formula: C12H8O4
• Molecular Weight: 216.19000
• Mol file: 38303-39-8.mol

Synonyms:

Chemical Property of Azulene-1,3-dicarboxylic acid

Chemical Property:

• PSA: 74.60000
• LogP: 2.18780

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Azulene-1,3-dicarboxylic acid

There total 11 articles about Azulene-1,3-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,3-bis(trifluoroacetyl)azulene (73017-87-5) → Azulen-1,3-dicarbonsaeure (38303-39-8)

Guidance literature:

With potassium hydroxide; In ethanol; water; at 50 - 60 ℃; for 8h;

DOI:10.1021/jo01297a041

Reference yield:

azulene (275-51-4) → Azulen-1,3-dicarbonsaeure (38303-39-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / 12 h / Ambient temperature

2: 95 percent / KOH / ethanol; H₂O / 8 h / 50 - 60 °C

With potassium hydroxide; In ethanol; water;

DOI:10.1021/jo01297a041

Reference yield:

diethyl (azulene)-1,3-dicarboxylate (36044-39-0) → Azulen-1,3-dicarbonsaeure (38303-39-8)

Guidance literature:

With potassium hydroxide; In ethanol;

DOI:10.1246/bcsj.35.1179

upstream raw materials:

azulene-1,3-dicarbaldehyde

1,3-bis(trifluoroacetyl)azulene

diethyl (azulene)-1,3-dicarboxylate

azulene

Refernces

• 1、 Zielinski, Tomasz,Kedziorek, Mariusz,Jurczak, Janusz. "Bisamides derived from azulene-1,3- and -5,7-dicarboxylic acids as new building blocks for anion receptors". . p. 838 - 846. Retrieved 2008/12/21.