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YE-120

Base Information
  • Chemical Name:YE-120
  • CAS No.:383124-82-1
  • Molecular Formula:C16H9Cl2N3O
  • Molecular Weight:330.16800
  • Hs Code.:
  • Mol file:383124-82-1.mol
YE-120

Synonyms:2-Dicyanmethylen-3-cyan-4,6-dimethyl-1,2-dihydro-pyridin;Fatostatin A;3-cyano-2-dicyanomethylene-4,6-dimethyl-1,2-dihydropyridine;1,2-Dihydro-2-dicyanmethylen-3-cyan-4,6-dimethylpyridin;

Suppliers and Price of YE-120
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • YE 120
  • 10mg
  • $ 502.00
  • TRC
  • YE-120
  • 100mg
  • $ 1175.00
  • Tocris
  • YE120 ≥98%(HPLC)
  • 10
  • $ 210.00
  • Tocris
  • YE120 ≥98%(HPLC)
  • 50
  • $ 846.00
  • Medical Isotopes, Inc.
  • YE-120
  • 10 mg
  • $ 640.00
  • Cayman Chemical
  • YE 120
  • 5mg
  • $ 160.00
  • Cayman Chemical
  • YE 120
  • 1mg
  • $ 54.00
  • ApexBio Technology
  • YE120
  • 50mg
  • $ 1305.00
  • ApexBio Technology
  • YE120
  • 10mg
  • $ 322.00
  • AK Scientific
  • 2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethylfuran-2-ylidene]propanedinitrile
  • 5mg
  • $ 298.00
Total 22 raw suppliers
Chemical Property of YE-120
Chemical Property:
  • PSA:80.60000 
  • LogP:4.38014 
Purity/Quality:

99%, *data from raw suppliers

YE 120 *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Uses YE-120 is a GPR35 agonist (EC50 = 32 nM in DMR assays). YE-120 also displays partial agonist activity in a β-arrestin translocation assay (EC50 = 10.2 μM). GPR35 is a Class A, rhodopsin-like G protein-coupled receptor which is predominantly expressed in immune and gastrointestinal tissue, with notable expression in the ileum (rat and human GPR35), the spleen (rat and murine GPR35) and the pancreas (human GPR35).
Technology Process of YE-120

There total 2 articles about YE-120 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With ethanol; lithium ethoxide; In tetrahydrofuran; Reflux;

Reference yield:

Guidance literature:
With lithium ethoxide; In ethanol; at 70 ℃; for 16h;
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