1-Bromomethylsulfinyl-4-chlorobenzene

Base Information

• Chemical Name: 1-Bromomethylsulfinyl-4-chlorobenzene
• CAS No.: 38325-81-4
• Molecular Formula: C7H6BrClOS
• Molecular Weight: 253.547
• DSSTox Substance ID: DTXSID30576324
• Mol file: 38325-81-4.mol

Synonyms:1-bromomethylsulfinyl-4-chlorobenzene;38325-81-4;4-Chloro-1-(bromomethylsulfinyl)-benzene;SCHEMBL10739677;DTXSID30576324;NREWMOFWMRQRPT-UHFFFAOYSA-N;1-(Bromomethanesulfinyl)-4-chlorobenzene

Chemical Property of 1-Bromomethylsulfinyl-4-chlorobenzene

Chemical Property:

• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 251.90113
• Heavy Atom Count: 11
• Complexity: 145

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1S(=O)CBr)Cl

Technology Process of 1-Bromomethylsulfinyl-4-chlorobenzene

There total 2 articles about 1-Bromomethylsulfinyl-4-chlorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

(bromomethyl)(4-chlorophenyl)sulfane (83767-73-1) → 1-bromomethylsulfinyl-4-chlorobenzene (38325-81-4)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; Ambient temperature;

DOI:10.1016/0223-5234(93)90014-6

Reference yield:

(bromomethyl)(4-chlorophenyl)sulfane (83767-73-1) + potassium carbonate (584-08-7) → 1-bromomethylsulfinyl-4-chlorobenzene (38325-81-4)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform;

Reference yield:

5-chloropyrimidin-2-one (54326-16-8) + 1-bromomethylsulfinyl-4-chlorobenzene (38325-81-4) → 5-chloro-1-(4-chlorophenylsulfinyl)methyl-2(1H)-pyrimidinone

Guidance literature:

With potassium tert-butylate; Yield given. Multistep reaction; 1.) DMF, RT, 10 min, 2.) DMF, 60 deg C, 2 d;

DOI:10.1016/0223-5234(93)90014-6

upstream raw materials:

(bromomethyl)(4-chlorophenyl)sulfane

potassium carbonate

Downstream raw materials:

methyl 4-chlorophenyl sulfoxide