2-Chloro-4-phenyl-6-(P-tolyl)nicotinonitrile

Base Information

Chemical Name:2-Chloro-4-phenyl-6-(P-tolyl)nicotinonitrile
CAS No.:38477-47-3
Molecular Formula:C19H13ClN2
Molecular Weight:304.77300
Hs Code.:
DSSTox Substance ID:DTXSID60576796
Wikidata:Q82466662
Mol file:38477-47-3.mol

Synonyms:38477-47-3;2-CHLORO-4-PHENYL-6-(P-TOLYL)NICOTINONITRILE;DTXSID60576796;2-Chloro-6-(4-methylphenyl)-4-phenylpyridine-3-carbonitrile

Suppliers and Price of 2-Chloro-4-phenyl-6-(P-tolyl)nicotinonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Chloro-4-phenyl-6-(p-tolyl)nicotinonitrile 97%
1g
$ 579.00

Total 0 raw suppliers

Chemical Property of 2-Chloro-4-phenyl-6-(P-tolyl)nicotinonitrile

Chemical Property:

PSA：36.68000
LogP:5.24908
XLogP3:5.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:304.0767261
Heavy Atom Count:22
Complexity:401

Purity/Quality:: 2-Chloro-4-phenyl-6-(p-tolyl)nicotinonitrile 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NC(=C(C(=C2)C3=CC=CC=C3)C#N)Cl

Technology Process of 2-Chloro-4-phenyl-6-(P-tolyl)nicotinonitrile

There total 1 articles about 2-Chloro-4-phenyl-6-(P-tolyl)nicotinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 38477-47-3
2-chloro-4-phenyl-6-p-tolyl-nicotinonitrile

Guidance literature:: 2-Pyridon IIIc, POCl3;

Reference yield: 91.0%

: 38477-47-3
2-chloro-4-phenyl-6-p-tolyl-nicotinonitrile

: 623-51-8
ethyl 2-sulfanylacetate

: 94360-76-6
(3-Cyano-4-phenyl-6-p-tolyl-pyridin-2-ylsulfanyl)-acetic acid ethyl ester

Guidance literature:: With potassium hydroxide; In N,N-dimethyl-formamide; at 60 - 65 ℃; for 14h;

Reference yield:

: 38477-47-3
2-chloro-4-phenyl-6-p-tolyl-nicotinonitrile

: 94360-82-4
3-Amino-4-phenyl-6-p-tolyl-thieno[2,3-b]pyridine-2-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / 50percent aq. KOH / dimethylformamide / 14 h / 60 - 65 °C

2: sodium ethoxide / ethanol / 8 h / 60 - 65 °C

With potassium hydroxide; sodium ethanolate; In ethanol; N,N-dimethyl-formamide;