Technology Process of Ethenamine, 2-[(S)-cyclohexylsulfinyl]-N,N-dimethyl-1-(2-propenylthio)-,
(1Z)-
There total 3 articles about Ethenamine, 2-[(S)-cyclohexylsulfinyl]-N,N-dimethyl-1-(2-propenylthio)-,
(1Z)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(R)-2-(Cyclohexylsulfinyl)-N,N-dimethylethanethioamide;
With
tert.-butyl lithium;
In
tetrahydrofuran; pentane;
at -40 ℃;
for 1h;
allyl bromide;
In
tetrahydrofuran; pentane;
at -40 - 20 ℃;
for 1.5h;
DOI:10.1021/jo035488b
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 83 percent / pyridine / tetrahydrofuran / 2.5 h / -50 °C
2.1: NaHMDS / tetrahydrofuran / 1.5 h / -78 °C
3.1: t-BuLi / tetrahydrofuran; pentane / -40 - 0 °C
3.2: tetrahydrofuran; pentane / 1.5 h / -40 - 20 °C
With
pyridine; tert.-butyl lithium; sodium hexamethyldisilazane;
In
tetrahydrofuran; pentane;
DOI:10.1021/jo015956m
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: NaHMDS / tetrahydrofuran / 1.5 h / -78 °C
2.1: t-BuLi / tetrahydrofuran; pentane / -40 - 0 °C
2.2: tetrahydrofuran; pentane / 1.5 h / -40 - 20 °C
With
tert.-butyl lithium; sodium hexamethyldisilazane;
In
tetrahydrofuran; pentane;
DOI:10.1021/jo015956m
