1-pentofuranosyl-1H-imidazo[1,2-b]pyrazole-7-carboxamide

Base Information

Chemical Name:1-pentofuranosyl-1H-imidazo[1,2-b]pyrazole-7-carboxamide
CAS No.:91296-28-5
Molecular Formula:C₁₁H₁₄N₄O₅
Molecular Weight:282.256
Hs Code.:

Synonyms:NSC370401

Suppliers and Price of 1-pentofuranosyl-1H-imidazo[1,2-b]pyrazole-7-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-pentofuranosyl-1H-imidazo[1,2-b]pyrazole-7-carboxamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.97g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-pentofuranosyl-1H-imidazo[1,2-b]pyrazole-7-carboxamide

There total 4 articles about 1-pentofuranosyl-1H-imidazo[1,2-b]pyrazole-7-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 91296-23-0
1-β-D-ribofuranosylimidazo<1,2-b>pyrazole-7-carbonitrile

: 91296-28-5
1-β-D-ribofuranosylimidazo<1,2-b>pyrazole-7-carboxamide

Guidance literature:: With ammonium hydroxide; dihydrogen peroxide; for 16h; Ambient temperature;
DOI:10.1021/jo00193a017

Reference yield:

: 91296-19-4
imidazo<1,2-b>pyrazole-7-carbonitrile

: 91296-28-5
1-β-D-ribofuranosylimidazo<1,2-b>pyrazole-7-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1) hexamethyldisilazane, (NH₄)2SO₄ 2) trimethylsilyl trifluoromethanesulfonate / 1) reflux, 3h 2) CH₃CN, ambient temp., 3d (isomeric ratio varies with reaction time)

2: 70 percent / NH₃ / methanol / 16 h / Ambient temperature

3: 75 percent / 30percent H₂O₂ / NH₄OH / 16 h / Ambient temperature

With ammonium sulfate; ammonium hydroxide; trimethylsilyl trifluoromethanesulfonate; ammonia; dihydrogen peroxide; 1,1,1,3,3,3-hexamethyl-disilazane; In methanol;
DOI:10.1021/jo00193a017

Reference yield:

: 91296-17-2
5-amino-1-(2,2-diethoxyethyl)-1H-pyrazole-4-carbonitrile

: 91296-28-5
1-β-D-ribofuranosylimidazo<1,2-b>pyrazole-7-carboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: 60 percent / 1N HCl / 0.5 h / Heating

2: 1) hexamethyldisilazane, (NH₄)2SO₄ 2) trimethylsilyl trifluoromethanesulfonate / 1) reflux, 3h 2) CH₃CN, ambient temp., 3d (isomeric ratio varies with reaction time)

3: 70 percent / NH₃ / methanol / 16 h / Ambient temperature

4: 75 percent / 30percent H₂O₂ / NH₄OH / 16 h / Ambient temperature

With hydrogenchloride; ammonium sulfate; ammonium hydroxide; trimethylsilyl trifluoromethanesulfonate; ammonia; dihydrogen peroxide; 1,1,1,3,3,3-hexamethyl-disilazane; In methanol;
DOI:10.1021/jo00193a017