8-Oxomyristic acid

Base Information

• Chemical Name: 8-Oxomyristic acid
• CAS No.: 39747-88-1
• Molecular Formula: C14H26O3
• Molecular Weight: 242.35400
• Mol file: 39747-88-1.mol

Synonyms:8CO-Myristic acid;8-Oxomyristic acid;

Chemical Property of 8-Oxomyristic acid

Chemical Property:

• PSA: 54.37000
• LogP: 3.95110

Purity/Quality:

99% ^*data from raw suppliers

8-OxotetradecanoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 8-Oxotetradecanoic Acid is an intermediate used to synthesize 8-Hydroxytetradecanoic Acid (H954200) which is a metabolite of hydroxystearic acid.

Technology Process of 8-Oxomyristic acid

There total 8 articles about 8-Oxomyristic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

n-tetradecanoic acid (544-63-8) + trifluoroacetic acid (76-05-1) → 9-oxo-tetradecanoic acid (71173-32-5) + 11-Oxomyristinsaeure (2388-80-9) + 7-Oxo-myristinsaeure (54527-27-4) + 8-Oxotetradecanoic acid (39747-88-1)

Guidance literature:

With tert-butylammonium hexafluorophosphate(V); In dichloromethane; Yield given. Further byproducts given. Yields of byproduct given;

Reference yield:

1-n-hexylcyclooctanol (76182-96-2) → 8-Oxotetradecanoic acid (39747-88-1)

Guidance literature:

With ruthenium trichloride; sodium periodate; toluene-4-sulfonic acid; Yield given. Multistep reaction; 1.) benzene, reflux, overnight, 2.) CH₃CN, CCl₄, H₂O, r.t., 7.5 d;

DOI:10.1021/jo00081a027

Reference yield:

cycloactanone (502-49-8) → 8-Oxotetradecanoic acid (39747-88-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Mg, I₂ / 1.) THF, 15 min, 2.) r.t., overnight

2: 1.) p-TsOH, 2.) RuCl₃*xH₂O, NaIO₄ / 1.) benzene, reflux, overnight, 2.) CH₃CN, CCl₄, H₂O, r.t., 7.5 d

With ruthenium trichloride; sodium periodate; iodine; toluene-4-sulfonic acid; magnesium;

DOI:10.1021/jo00081a027

upstream raw materials:

n-tetradecanoic acid

trifluoroacetic acid

1-n-hexylcyclooctanol

cycloactanone

Downstream raw materials:

O⁴-Benzyl-N-(tert-butyloxycarbonyl)neoenactin A

O,O-Dibenzyl-N-(tert-butyloxycarbonyl)neoenactin A

Neoenactin A