[1,1'-Biphenyl]-3,3',5,5'-tetrol

Base Information

• Chemical Name: [1,1'-Biphenyl]-3,3',5,5'-tetrol
• CAS No.: 531-02-2
• Molecular Formula: C12H10 O4
• Molecular Weight: 218.209
• Hs Code.: 2906299090
• European Community (EC) Number: 208-500-2
• UNII: B7CAU2QQ8O
• DSSTox Substance ID: DTXSID0060195
• Nikkaji Number: J6.976K
• Wikidata: Q27274460
• Mol file: 531-02-2.mol

Synonyms:Diresorcinol;531-02-2;[1,1'-Biphenyl]-3,3',5,5'-tetrol;5-(3,5-dihydroxyphenyl)benzene-1,3-diol;[1,1'-biphenyl]-3,3',5,5'-tetraol;UNII-B7CAU2QQ8O;B7CAU2QQ8O;(1,1'-Biphenyl)-3,3',5,5'-tetrol;EINECS 208-500-2;(1,1'-Biphenyl)-3,3',5,5'-tetraol;Diresorcin;DIRESORCINOL [MI];5,5'-BIRESORCINOL;SCHEMBL337732;DTXSID0060195;3,5,3',5'-TETRAHYDROXYDIPHENYL;(1,1-BIPHENYL)-3,3,5,5-TETROL;EN300-5477514;Q27274460

Chemical Property of [1,1'-Biphenyl]-3,3',5,5'-tetrol

Chemical Property:

• Melting Point: 310°
• Refractive Index: 1.7160 (estimate)
• Boiling Point: 514.6°Cat760mmHg
• PKA: 8.78±0.10(Predicted)
• Flash Point: 261.7°C
• PSA: 80.92000
• Density: 1.47g/cm³
• LogP: 2.17600
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 218.05790880
• Heavy Atom Count: 16
• Complexity: 189

Purity/Quality:

99%, ^*data from raw suppliers

DIRESORCINOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C=C1O)O)C2=CC(=CC(=C2)O)O
• Use Description: [1,1'-biphenyl]-3,3',5,5'-tetraol, also known as hydroxybiphenyl, has applications in various fields. In the pharmaceutical and medicinal sector, it serves as a key intermediate in the synthesis of pharmaceutical compounds with potential therapeutic properties. Its role is pivotal in the structural modification of molecules, enabling the creation of novel drug candidates for various medical conditions. Additionally, in academic research and organic chemistry, this compound can be utilized as a building block for the synthesis of complex organic molecules, facilitating studies in chemical synthesis and chemical biology. Moreover, in the field of materials science, it may find applications in the development of specialty polymers and materials due to its unique chemical structure. Its diverse uses underscore its importance in drug discovery, chemical research, and the potential enhancement of material properties across these fields.

Technology Process of [1,1'-Biphenyl]-3,3',5,5'-tetrol

There total 4 articles about [1,1'-Biphenyl]-3,3',5,5'-tetrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,5,3',5'-tetramethoxybiphenyl (108840-33-1) → 3,3',5,5'-tetrahydroxy-1,1'-biphenyl (531-02-2)

Guidance literature:

With boron tribromide; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1039/c3ce40761f

Reference yield:

NaHCO3 + BBr3 + 3,5,3',5'-tetramethoxybiphenyl (108840-33-1) → 3,3',5,5'-tetrahydroxy-1,1'-biphenyl (531-02-2)

Guidance literature:

Reference yield:

recorcinol (108-46-3) → 3,3',5,5'-tetrahydroxy-1,1'-biphenyl (531-02-2)

Guidance literature:

With sodium hydroxide; Zerlegen der Schmelze mit verd. Schwefelsaeure und Ausschuetteln mit Aether; Behandeln des Rueckstandes mit Wasser;

upstream raw materials:

recorcinol

3,5,3',5'-tetramethoxybiphenyl

Downstream raw materials:

biphenyl

Refernces

• 1、 -. "BIPHENYL IODINATED DERIVATIVES AND THEIR DIAGNOSTIC USE". . . Retrieved 2008/06/13.