3-fluoro-N-(4-methylphenyl)benzamide

Base Information

• Chemical Name: 3-fluoro-N-(4-methylphenyl)benzamide
• CAS No.: 398-80-1
• Molecular Formula: C14H12FNO
• Molecular Weight: 229.254
• DSSTox Substance ID: DTXSID80356850
• Nikkaji Number: J879.353K
• Wikidata: Q82136456
• Mol file: 398-80-1.mol

Synonyms:3-fluoro-N-(4-methylphenyl)benzamide;398-80-1;benzamide,3-fluoro-n-(4-methylphenyl)-;SCHEMBL8361568;3-Fluoro-N-(p-tolyl)benzamide;DTXSID80356850;AKOS001081387;AN-652/11384814;Z28134844

Chemical Property of 3-fluoro-N-(4-methylphenyl)benzamide

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 229.090292168
• Heavy Atom Count: 17
• Complexity: 261

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)NC(=O)C2=CC(=CC=C2)F

Technology Process of 3-fluoro-N-(4-methylphenyl)benzamide

There total 1 articles about 3-fluoro-N-(4-methylphenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

m-Fluorobenzonitrile (403-54-3) + bis(4-methylphenyl)iodonium trifluoromethanesulfonate (123726-16-9) → 3-fluoro-N-(4-methylphenyl)benzamide (398-80-1)

Guidance literature:

With copper diacetate; In water; 1,2-dichloro-ethane; at 80 ℃; for 20h; Schlenk technique; Sealed tube;

upstream raw materials:

m-Fluorobenzonitrile

bis(4-methylphenyl)iodonium trifluoromethanesulfonate