5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione

Base Information

Chemical Name:5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione
CAS No.:143790-05-0
Molecular Formula:C₈H₉FN₂O₄S
Molecular Weight:248.235
Hs Code.:
European Community (EC) Number:875-647-2
UNII:7D832RLM83
DSSTox Substance ID:DTXSID10932106
Nikkaji Number:J524.974K
Wikidata:Q82907768
ChEMBL ID:CHEMBL301450
Mol file:143790-05-0.mol

Synonyms:2',3',5-FTU;2',3'-dideoxy-5-fluoro-3'-thiauridine

Suppliers and Price of 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：98.76000
Density:1.65g/cm³
LogP:-0.67700
Solubility.:N,N-Dimethylformamide, Methanol, Tetrahydrofuran
XLogP3:-0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:248.02670611
Heavy Atom Count:16
Complexity:362

Purity/Quality:: 95%+ or 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(OC(S1)CO)N2C=C(C(=O)NC2=O)F
Isomeric SMILES:C1[C@H](O[C@H](S1)CO)N2C=C(C(=O)NC2=O)F
Uses 2',3'-dideoxy-5-fluoro-3'-thiauridine can be used as antiviral nucleoside analog, Inhibition of human immunodeficiency and hepatitis B viruses.

Technology Process of 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione

There total 2 articles about 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.4%