Technology Process of Sampangine
There total 10 articles about Sampangine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
N,N-dimethyl-formamide dimethyl acetal; cleistopholine;
In
DMF (N,N-dimethyl-formamide);
at 120 ℃;
for 0.5h;
With
ammonium chloride; acetic acid;
In
DMF (N,N-dimethyl-formamide);
at 120 ℃;
for 0.5h;
- Guidance literature:
-
With
2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 18h;
regioselective reaction;
Inert atmosphere;
Schlenk technique;
DOI:10.1002/ejoc.201403502
