4-(4,10-dihydro-10-oxothieno(3,2-c)(1)benzoxepin-8-yl)butyric acid

Base Information

Chemical Name:4-(4,10-dihydro-10-oxothieno(3,2-c)(1)benzoxepin-8-yl)butyric acid
CAS No.:88358-30-9
Molecular Formula:C₁₆H₁₄O₄S
Molecular Weight:302.351
Hs Code.:2934999090
Mol file:88358-30-9.mol

Synonyms:4-(4,10-dihydro-10-oxothieno(3,2-c)(1)benzoxepin-8-yl)butyric acid

Suppliers and Price of 4-(4,10-dihydro-10-oxothieno(3,2-c)(1)benzoxepin-8-yl)butyric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of 4-(4,10-dihydro-10-oxothieno(3,2-c)(1)benzoxepin-8-yl)butyric acid

Chemical Property:

Vapor Pressure:4.36E-13mmHg at 25°C
Boiling Point:553.5°C at 760 mmHg
Flash Point:288.6°C
PSA：91.84000
Density:1.366g/cm³
LogP:3.27880

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-(4,10-dihydro-10-oxothieno(3,2-c)(1)benzoxepin-8-yl)butyric acid

There total 4 articles about 4-(4,10-dihydro-10-oxothieno(3,2-c)(1)benzoxepin-8-yl)butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 88358-29-6
3-[4-(3-Carboxy-propyl)-phenoxymethyl]-thiophene-2-carboxylic acid

: 88358-30-9
4-(4,10-dihydro-10-oxothieno<3,2-c><1>bezoxepin-8-yl)butyric acid

Guidance literature:: With trifluoroacetic anhydride; In dichloromethane; for 4h; Heating;
DOI:10.1021/jm00369a023

Reference yield:

: 62889-58-1
4-(4-hydroxyphenyl)butyric acid ethyl ester

: 88358-30-9
4-(4,10-dihydro-10-oxothieno<3,2-c><1>bezoxepin-8-yl)butyric acid

Guidance literature:: Multi-step reaction with 3 steps

1: K₂CO₃, KI / butan-2-one / 24 h / Heating

2: aq. KOH / aq. ethanol / 3 h / Heating

3: 73 percent / TFAA / CH₂Cl₂ / 4 h / Heating

With potassium hydroxide; potassium carbonate; trifluoroacetic anhydride; potassium iodide; In ethanol; dichloromethane; butanone;
DOI:10.1021/jm00369a023

Reference yield:

: 59961-15-8
methyl 3-(bromomethyl)thiophene-2-carboxylate

: 88358-30-9
4-(4,10-dihydro-10-oxothieno<3,2-c><1>bezoxepin-8-yl)butyric acid

Guidance literature:: Multi-step reaction with 3 steps

1: K₂CO₃, KI / butan-2-one / 24 h / Heating

2: aq. KOH / aq. ethanol / 3 h / Heating

3: 73 percent / TFAA / CH₂Cl₂ / 4 h / Heating

With potassium hydroxide; potassium carbonate; trifluoroacetic anhydride; potassium iodide; In ethanol; dichloromethane; butanone;
DOI:10.1021/jm00369a023