AR-L 113 BS

Base Information

• Chemical Name: AR-L 113 BS
• CAS No.: 77414-25-6
• Molecular Formula: C14H13 N3 O S
• Molecular Weight: 271.343
• Mol file: 77414-25-6.mol

Synonyms:1H-Imidazo[4,5-b]pyridine,2-[2-methoxy-4-(methylthio)phenyl]- (9CI); AR-L 113BS; EMD 46512

Chemical Property of AR-L 113 BS

Chemical Property:

• PSA: 76.10000
• LogP: 3.35540

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of AR-L 113 BS

There total 2 articles about AR-L 113 BS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

sulmazole (73384-60-8,114046-29-6,114046-30-9) → 2-(2'-methoxy-4'-methylmercapto-phenyl)-1H-imidazo[4,5-b]pyridine (77414-25-6)

Guidance literature:

With fac-tris(2-phenylpyridinato-N,C₂')iridium(III); triphenylphosphine; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere; Irradiation;

DOI:10.1021/acscatal.0c00690

Reference yield:

sulmazole (73384-60-8,114046-29-6,114046-30-9) → 2-(2-Methoxy-4-methylsulfanyl-phenyl)-3H-imidazo[4,5-b]pyridine (77414-25-6) + 2-(4-Methanesulfonyl-2-methoxy-phenyl)-3H-imidazo[4,5-b]pyridine (77414-24-5) + 2-(4-Methanesulfinyl-2-methoxy-phenyl)-3H-imidazo[4,5-b]pyridin-6-ol + 2-(4-Methanesulfonyl-2-methoxy-phenyl)-3H-imidazo[4,5-b]pyridin-6-ol + N-[5-(2-Hydroxy-ethyl)-2-(4-methanesulfinyl-2-methoxy-phenyl)-3H-imidazol-4-yl]-acetamide + N-[5-(2-Hydroxy-ethyl)-2-(4-methanesulfonyl-2-methoxy-phenyl)-3H-imidazol-4-yl]-acetamide

Guidance literature:

metabolism in man;

Reference yield: 92.0%

2-(2-Methoxy-4-methylsulfanyl-phenyl)-3H-imidazo[4,5-b]pyridine (77414-25-6) → 2-(4-Methanesulfonyl-2-methoxy-phenyl)-3H-imidazo[4,5-b]pyridine (77414-24-5)

Guidance literature:

With peracetic acid; In methanol; for 3h;

DOI:10.1021/jm00383a006

upstream raw materials:

sulmazole

sulmazole

Downstream raw materials:

sulmazole

2-(4-Methanesulfonyl-2-methoxy-phenyl)-3H-imidazo[4,5-b]pyridine

sulmazole