Technology Process of Benzenepropanoic acid, a-[[(1,1-dimethylethyl)sulfonyl]methyl]-,(aS)-
There total 4 articles about Benzenepropanoic acid, a-[[(1,1-dimethylethyl)sulfonyl]methyl]-,(aS)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Ru2Cl4((S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl)2*NEt3; hydrogen; triethylamine;
In
methanol; water;
at 80 ℃;
for 16h;
Yield given;
DOI:10.1139/cjc-76-9-1304
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 87 percent / K2CO3 / acetonitrile / 18 h / Ambient temperature
2: 88 percent / 1N aq. NaOH, benzyltriethylammonium chloride / 5 h / Heating
3: 96 percent / Na2WO4, 2N aq. H2SO4, 30 percent aq. H2O2 / methanol / 2 h / 60 °C
4: H2, Ru2Cl4<(-)-2,2'-bis(di-p-tolyl-phopshino-1,1'-binaphthyl>2Et3N, Et3N / methanol; H2O / 16 h / 80 °C
With
sodium hydroxide; sodium tungstate; Ru2Cl4((S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl)2*NEt3; sulfuric acid; N-benzyl-N,N,N-triethylammonium chloride; hydrogen; dihydrogen peroxide; potassium carbonate; triethylamine;
In
methanol; water; acetonitrile;
DOI:10.1139/cjc-76-9-1304
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 96 percent / Na2WO4, 2N aq. H2SO4, 30 percent aq. H2O2 / methanol / 2 h / 60 °C
2: H2, Ru2Cl4<(-)-2,2'-bis(di-p-tolyl-phopshino-1,1'-binaphthyl>2Et3N, Et3N / methanol; H2O / 16 h / 80 °C
With
sodium tungstate; Ru2Cl4((S)-(-)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl)2*NEt3; sulfuric acid; hydrogen; dihydrogen peroxide; triethylamine;
In
methanol; water;
DOI:10.1139/cjc-76-9-1304
