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Technology Process of KT 5720

KT 5720

Base Information
  • Chemical Name:KT 5720
  • CAS No.:108068-98-0
  • Molecular Formula:C32H31N3O5
  • Molecular Weight:537.61
  • Hs Code.:29419090
  • European Community (EC) Number:810-587-2
  • Pharos Ligand ID:5F57K4BWG8R9
  • Wikipedia:KT5720
  • Mol file:108068-98-0.mol
KT 5720

Synonyms:KT 5720;KT-5720;KT5720

Suppliers and Price of KT 5720
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • KT 5720
  • 100ug
  • $ 460.00
  • TRC
  • KT 5720
  • 2.5mg
  • $ 1400.00
  • Tocris
  • KT 5720 ≥98%(HPLC)
  • 100U
  • $ 203.00
  • Sigma-Aldrich
  • KT 5720 ≥98% (HPLC), powder
  • .1mg
  • $ 209.00
  • Sigma-Aldrich
  • KT5720
  • 100ug
  • $ 181.00
  • Sigma-Aldrich
  • KT5720
  • 50ug
  • $ 124.00
  • Sigma-Aldrich
  • InSolution? KT5720
  • 50ug
  • $ 124.00
  • Sigma-Aldrich
  • InSolution KT5720 - CAS 108068-98-0 - Calbiochem
  • 50 μg
  • $ 119.32
  • Sigma-Aldrich
  • KT 5720 ≥98% (HPLC), powder
  • 0.1 mg
  • $ 217.00
  • ChemScene
  • KT 5720 ≥99.0%
  • 100ug
  • $ 740.00
Total 19 raw suppliers
Chemical Property of KT 5720
Chemical Property:
  • Vapor Pressure:1.88E-21mmHg at 25°C 
  • Refractive Index:1.752 
  • Boiling Point:715 °C at 760 mmHg 
  • PKA:11.96±0.40(Predicted) 
  • Flash Point:386.2 °C 
  • PSA：94.72000 
  • Density:1.49 g/cm3 
  • LogP:5.93440 
  • Storage Temp.:−20°C 
  • Solubility.:methanol: 5 mg/mL 
  • XLogP3:5.1
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:5
  • Rotatable Bond Count:7
  • Exact Mass:537.22637110
  • Heavy Atom Count:40
  • Complexity:1060
Purity/Quality:

98%,99%, *data from raw suppliers

KT 5720 *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi 
  • Hazard Codes:Xi 
  • Statements: 36/38 
  • Safety Statements: 26-36 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:CCCCCCOC(=O)C1(CC2N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N(C7=C53)C1(O2)C)CNC6=O)O
  • Isomeric SMILES:CCCCCCOC(=O)[C@]1(C[C@H]2N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N(C7=C53)[C@@]1(O2)C)CNC6=O)O
  • Description Protein kinase A (PKA) regulates multiple signal transduction events via protein phosphorylation and is integral to all cellular responses involving the cyclic AMP second messenger system. KT 5720 is one of a family of compounds synthesized by the fungus Nocardiopsis sp. It blocks PKA signaling through competitive inhibition of ATP with a Ki value of 60 nM. Reported IC50 values vary widely depending upon ATP concentration tested and can range from 56 nM (low ATP) to 3 μM (physiologic ATP). Non-specific effects of KT 5720 include inhibition of phosphorylase kinase, PDK1, MEK, MSK1, PKBα, and GSK3β at concentrations as effective as or more potent than that for inhibition of PKA.
  • Uses KT 5720 is a potent, specific and cell-permeable inhibitor of PKA.
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Total 8 Pictures about this product