{[(2S)-2-azaniumyl-4-methylpentanoyl]amino}acetate

Base Information

Chemical Name:{[(2S)-2-azaniumyl-4-methylpentanoyl]amino}acetate
CAS No.:686-50-0
Molecular Formula:C8H16 N2 O3
Molecular Weight:188.227
Hs Code.:2924199090
Mol file:686-50-0.mol

Synonyms:LG zwitterion;Leu-Gly zwitterion;L-Leu-Gly zwitterion;leucylglycine zwitterion;L-leucylglycine zwitterion;CHEBI:133658;{[(2S)-2-azaniumyl-4-methylpentanoyl]amino}acetate

Suppliers and Price of {[(2S)-2-azaniumyl-4-methylpentanoyl]amino}acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Leu-Gly-OH
2g
$ 333.00

TRC
H-Leu-Gly-OH
2mg
$ 60.00

TCI Chemical
L-Leucylglycine Hydrate
100mg
$ 43.00

Sigma-Aldrich
Leu-Gly
1g
$ 114.00

Sigma-Aldrich
Leu-Gly
5g
$ 263.00

Crysdot
H-Leu-Gly-OH 95+%
25g
$ 324.00

Chem-Impex
Leu-Gly-OH,99%(HPLC) 99%(HPLC)
1G
$ 50.40

Chem-Impex
Leu-Gly-OHhydrochloride
1G
$ 18.05

Chem-Impex
Leu-Gly-OHhydrochloride
25G
$ 301.68

Chem-Impex
Leu-Gly-OHhydrochloride
5G
$ 72.33

Total 47 raw suppliers

Chemical Property of {[(2S)-2-azaniumyl-4-methylpentanoyl]amino}acetate

Chemical Property:

Melting Point:~245 °C (dec.)
Refractive Index:86 ° (C=2, H2O)
Boiling Point:323.23°C (rough estimate)
PKA:3.25(at 25℃)
PSA：92.42000
Density:1.1793 (rough estimate)
LogP:0.65180
Storage Temp.:−20°C
XLogP3:-1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:188.11609238
Heavy Atom Count:13
Complexity:186

Purity/Quality:

97% ^*data from raw suppliers

Leu-Gly-OH ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(C)CC(C(=O)NCC(=O)[O-])[NH3+]
Isomeric SMILES:CC(C)C[C@@H](C(=O)NCC(=O)[O-])[NH3+]
Uses This dipeptide inhibits the ubiquitin-mediated proteolysis.

Technology Process of {[(2S)-2-azaniumyl-4-methylpentanoyl]amino}acetate

There total 18 articles about {[(2S)-2-azaniumyl-4-methylpentanoyl]amino}acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 51220-76-9
(N-(tert-butoxycarbonyl)-L-leucinyl)glycine ethyl ester

: 686-50-0
L-leucyl-glycine

: 5815-67-8,5845-67-0,108315-75-9
cyclo(glycyl-L-leucyl)

Guidance literature:: With water; In N,N-dimethyl-formamide; at 150 ℃; for 2.5h; enantioselective reaction; Microwave irradiation;
DOI:10.1016/j.bioorg.2010.05.002

Reference yield: 87.1%

: 72-18-4,25609-85-2,7004-03-7,921-10-8
L-valine

: 3190-70-3,26334-33-8,51018-87-2,51248-35-2
L-Leucin-N-carbonsaeureanhydrid

: 61-90-5,21675-61-6,25248-98-0,70-45-1
L-leucine

: 686-50-0
L-leucyl-glycine

: 462-60-2
N-carbamoylglycine

Guidance literature:: With water; potassium hydroxide; potassium borate buffer; at 3 ℃; Product distribution; effect of use of various amino acid and NCA with various concentrations; effect of use various temp.; extent of hydrolysis;