Technology Process of Octanal,
8-[(4-methoxyphenyl)methoxy]-5-oxo-3-[(phenylmethoxy)methyl]-
There total 6 articles about Octanal,
8-[(4-methoxyphenyl)methoxy]-5-oxo-3-[(phenylmethoxy)methyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
6-benzyloxymethyl-1-(4-methoxy-benzyloxy)-non-8-en-4-one;
With
osmium(VIII) oxide; 4-methylmorpholine N-oxide;
In
water; acetone;
at 20 ℃;
With
sodium periodate;
In
water; acetone;
at 20 ℃;
Further stages.;
DOI:10.1021/ol0171618
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: magnesium / tetrahydrofuran
1.2: 85 percent / tetrahydrofuran / 20 °C
2.1: 90 percent / oxalyl chloride; dimethylsulfoxide; triethylamine / CH2Cl2 / -78 °C
3.1: osmium tetroxide; 4-methylmorpholine N-oxide / acetone; H2O / 20 °C
3.2: 85 percent / sodium periodate / acetone; H2O / 20 °C
With
osmium(VIII) oxide; oxalyl dichloride; magnesium; dimethyl sulfoxide; 4-methylmorpholine N-oxide; triethylamine;
In
tetrahydrofuran; dichloromethane; water; acetone;
1.2: Grignard reaction / 2.1: Swern oxidation;
DOI:10.1021/ol0171618
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: magnesium / tetrahydrofuran
1.2: 85 percent / tetrahydrofuran / 20 °C
2.1: 90 percent / oxalyl chloride; dimethylsulfoxide; triethylamine / CH2Cl2 / -78 °C
3.1: osmium tetroxide; 4-methylmorpholine N-oxide / acetone; H2O / 20 °C
3.2: 85 percent / sodium periodate / acetone; H2O / 20 °C
With
osmium(VIII) oxide; oxalyl dichloride; magnesium; dimethyl sulfoxide; 4-methylmorpholine N-oxide; triethylamine;
In
tetrahydrofuran; dichloromethane; water; acetone;
1.2: Grignard reaction / 2.1: Swern oxidation;
DOI:10.1021/ol0171618
