Tert-butyl 3-formyl-4-hydroxyphenylcarbamate

Base Information

Chemical Name:Tert-butyl 3-formyl-4-hydroxyphenylcarbamate
CAS No.:402826-43-1
Molecular Formula:C12H15NO4
Molecular Weight:237.25200
Hs Code.:
DSSTox Substance ID:DTXSID60461294
Wikidata:Q82285572
Mol file:402826-43-1.mol

Synonyms:402826-43-1;tert-butyl 3-formyl-4-hydroxyphenylcarbamate;tert-Butyl (3-formyl-4-hydroxyphenyl)carbamate;Carbamic acid, (3-formyl-4-hydroxyphenyl)-, 1,1-dimethylethyl ester;TERT-BUTYL N-(3-FORMYL-4-HYDROXYPHENYL)CARBAMATE;starbld0009817;SCHEMBL2981356;DTXSID60461294;CRA82643;AKOS024156721;CS-0371691;F95405

Suppliers and Price of Tert-butyl 3-formyl-4-hydroxyphenylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 8 raw suppliers

Chemical Property of Tert-butyl 3-formyl-4-hydroxyphenylcarbamate

Chemical Property:

PSA：75.63000
LogP:2.62470
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:237.10010796
Heavy Atom Count:17
Complexity:285

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC(=C(C=C1)O)C=O

Technology Process of Tert-butyl 3-formyl-4-hydroxyphenylcarbamate

There total 6 articles about Tert-butyl 3-formyl-4-hydroxyphenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: acetic acid 4-tert-butoxycarbonylamino-2-diacetoxymethyl-phenyl ester

: 402826-43-1
tert-butyl (3-formyl-4-hydroxyphenyl)carbamate

Guidance literature:: With water; sodium hydroxide; In methanol; at 100 ℃; for 5h;

Reference yield:

: 24590-01-0
acetyloxy(2-acetyloxy-5-nitrophenyl)methyl acetate

: 402826-43-1
tert-butyl (3-formyl-4-hydroxyphenyl)carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / H₂ / Pd/C / ethanol; tetrahydrofuran / 4 h / 2327.17 Torr

2: CH₂Cl₂ / 8 h / 20 °C

3: 1.23 g / NaOH; water / methanol / 5 h / Heating

With sodium hydroxide; water; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; dichloromethane;
DOI:10.1002/ejic.200300959

Reference yield:

: 97-51-8
5-Nitrosalicylaldehyde

: 402826-43-1
tert-butyl (3-formyl-4-hydroxyphenyl)carbamate

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid / 1 h / 20 °C

2: hydrogen / palladium 10% on activated carbon / methanol / 1140.08 Torr

3: dichloromethane / Inert atmosphere

4: sodium hydroxide; water / methanol / 5 h / Reflux

With sulfuric acid; water; hydrogen; sodium hydroxide; palladium 10% on activated carbon; In methanol; dichloromethane;