Nitazoxanide Impurity

Base Information Edit

Chemical Name:Nitazoxanide Impurity
CAS No.:402848-76-4
Molecular Formula:C12H10N2O3S
Molecular Weight:262.289
Hs Code.:
Mol file:402848-76-4.mol

Synonyms:2-(1,3-thiazol-2-ylcarbamoyl)phenyl acetate;2-Acetoxy-benzoesaeure-thiazol-2-ylamid;2-acetoxy-benzoic acid thiazol-2-ylamide;

Suppliers and Price of Nitazoxanide Impurity

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Acetoxy-N-(2-thiazolyl)benzamide
100mg
$ 180.00

Total 2 raw suppliers

Chemical Property of Nitazoxanide Impurity Edit

Chemical Property:

Melting Point:140-142 °C
PKA:7.10±0.50(Predicted)
PSA：96.53000
Density:1.390±0.06 g/cm3(Predicted)
LogP:2.39370
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

>95% ^*data from raw suppliers

2-Acetoxy-N-(2-thiazolyl)benzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-Acetoxy-N-(2-thiazolyl)-benzamide is used in the synthesis of thiazolides as novel antiviral agents. Used in the inhibition of hepatitis C virus replication. Nitazoxanide Impurity

Technology Process of Nitazoxanide Impurity

There total 2 articles about Nitazoxanide Impurity which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 96-50-4
2-thiazolylamine

: 50-78-2,98201-60-6
aspirin

: 402848-76-4
2-acetoxybenzoyl-N-(thiazol-2-yl)amide

Guidance literature:: aspirin; With bis(trichloromethyl) carbonate; In tetrahydrofuran; at 20 ℃; for 0.166667h; Inert atmosphere;

With 2,4,6-trimethyl-pyridine; In tetrahydrofuran; for 0.5h; Inert atmosphere;

2-thiazolylamine; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; Inert atmosphere; Reflux;
DOI:10.1007/s00044-021-02843-1