Apogossypolic acid

Base Information

• Chemical Name: Apogossypolic acid
• CAS No.: 4741-50-8
• Molecular Formula: C₁₃H₁₆O₆
• Molecular Weight: 268.266
• Mol file: 4741-50-8.mol

Synonyms:3-Isopropyl-4,5-dimethoxy-phthalsaeure;Apogossypolsaeure;3-Isopropyl-4,5-dimethoxy-phthalic acid;

Chemical Property of Apogossypolic acid

Chemical Property:

• PSA: 93.06000
• LogP: 2.22360

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Apogossypolic acid

There total 7 articles about Apogossypolic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-isopropyl-4,5-dimethoxy-phthalic acid-anhydride → 3-isopropyl-4,5-dimethoxy-phthalic acid (4741-50-8)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/ja01276a048 DOI:10.1021/ja01874a039

Reference yield:

→ 3-isopropyl-4,5-dimethoxy-phthalic acid (4741-50-8)

Guidance literature:

With potassium permanganate; acetone;

DOI:10.1021/ja01276a048

Reference yield:

2-isopropyl-3,4-dimethoxy-benzoic acid (71596-66-2) → 3-isopropyl-4,5-dimethoxy-phthalic acid (4741-50-8)

Guidance literature:

Multi-step reaction with 5 steps

1: aqueous nitric acid

2: diethyl ether

3: Raney nickel; ethanol / Hydrogenation

4: ueber mehrere Stufen

5: aq. NaOH solution

With sodium hydroxide; diethyl ether; ethanol; nitric acid; nickel;

DOI:10.1021/ja01874a039

upstream raw materials:

2-isopropyl-3,4-dimethoxy-benzoic acid

6-amino-2-isopropyl-3,4-dimethoxy-benzoic acid methyl ester

2-isopropyl-3,4-dimethoxy-6-nitro-benzoic acid

2-isopropyl-3,4-dimethoxy-6-nitro-benzoic acid methyl ester

Downstream raw materials:

3,4-dihydroxy-5-isopropyl-benzoic acid