2-Amino-6-benzoyl-1-((isopropyl)sulphonyl)-1H-benzimidazole

Base Information

Chemical Name:2-Amino-6-benzoyl-1-((isopropyl)sulphonyl)-1H-benzimidazole
CAS No.:63197-61-5
Molecular Formula:C17H17N3O3S
Molecular Weight:343.406
Hs Code.:2933990090
European Community (EC) Number:263-995-2
DSSTox Substance ID:DTXSID80979205
Nikkaji Number:J327.014I
Wikidata:Q82964769
Mol file:63197-61-5.mol

Synonyms:63197-61-5;2-Amino-6-benzoyl-1-((isopropyl)sulphonyl)-1H-benzimidazole;EINECS 263-995-2;(2-amino-3-propan-2-ylsulfonylbenzimidazol-5-yl)-phenylmethanone;2-AMINO-6-BENZOYL-1-[(ISOPROPYL)SULPHONYL]-1H-BENZIMIDAZOLE;SCHEMBL10906292;DTXSID80979205;SXUXQJLILGMLOR-UHFFFAOYSA-N;1-isopropylsulfonyl-2-amino-6-benzoylbenzimidazole;2-Amino-6-benzoyl-1-[(isopropyl)sulfonyl]-1H-benzimidazole;6-Benzoyl-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-2-amine;[2-Imino-3-(propane-2-sulfonyl)-2,3-dihydro-1H-benzimidazol-5-yl](phenyl)methanone

Suppliers and Price of 2-Amino-6-benzoyl-1-((isopropyl)sulphonyl)-1H-benzimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
[2-Amino-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-6-yl]phenylmethanone
10mg
$ 670.00

Total 5 raw suppliers

Chemical Property of 2-Amino-6-benzoyl-1-((isopropyl)sulphonyl)-1H-benzimidazole

Chemical Property:

Vapor Pressure:4.39E-13mmHg at 25°C
Boiling Point:571.8°Cat760mmHg
Flash Point:299.6°C
PSA：104.16000
Density:1.38g/cm³
LogP:3.44670
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:343.09906259
Heavy Atom Count:24
Complexity:566

Purity/Quality:

99% ^*data from raw suppliers

[2-Amino-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-6-yl]phenylmethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)S(=O)(=O)N1C2=C(C=CC(=C2)C(=O)C3=CC=CC=C3)N=C1N
Uses [2-Amino-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-6-yl]phenylmethanone is an intermediate used in the synthesis of Zinviroxime (Z465300), which is the (Z)-isomer of Enviroxime (E559600). Zinviroxime is a benzimidazole derivative that inhibits rhinovirus multiplication.

Technology Process of 2-Amino-6-benzoyl-1-((isopropyl)sulphonyl)-1H-benzimidazole

There total 3 articles about 2-Amino-6-benzoyl-1-((isopropyl)sulphonyl)-1H-benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 506-68-3
bromocyane

: 88965-53-1
3-(isopropylsulfonyl)amino-4-aminobenzophenone

: 63197-61-5
1-isopropylsulfonyl-2-amino-6-benzoylbenzimidazole

Guidance literature:: With sodium hydroxide; sodium chloride; ammonium chloride; In isopropyl alcohol;

Reference yield:

: 10147-37-2
Isopropylsulfonyl chloride

: 52329-60-9
(2-amino-1H-benzimidazol-5-yl)(phenyl)methanone

: 63197-61-5
1-isopropylsulfonyl-2-amino-6-benzoylbenzimidazole

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) dimethoxyethane, RT, 1 h, 2.) dimethoxyethane, reflux, 4 h;
DOI:10.1021/jm00178a004