Indopanolol

Base Information

• Chemical Name: Indopanolol
• CAS No.: 69907-17-1
• Deprecated CAS: 128182-65-0
• Molecular Formula: C₂₀H₂₃ClN₂O₃
• Molecular Weight: 374.867
• UNII: 2JQ3661CAD
• ChEMBL ID: CHEMBL1742464
• DSSTox Substance ID: DTXSID501031596
• NCI Thesaurus Code: C65914
• Wikidata: Q17081544
• Wikipedia: Indopanolol
• Mol file: 69907-17-1.mol

Synonyms:Indopanolol;69907-17-1;Indopanolol [INN];2JQ3661CAD;1-[(3-chloro-2-methyl-1H-indol-4-yl)oxy]-3-(2-phenoxyethylamino)propan-2-ol;Indopanololum;UNII-2JQ3661CAD;SCHEMBL1255812;CHEMBL1742464;DTXSID501031596;(+-)-1-((3-Chlor-2-methyl-4-indolyl)oxy)-3-((2-phenoxyethyl)amino)-2-propanol;FT-0762797;Q17081544;(+-)-1-((3-Chloro-2-methylindol-4-yl)oxy)-3-((2-phenoxyethyl)amino)-2-propanol;(+-)-1-((3-Chloro-3-methylindol-4-yl)oxy)-3-((2-phenoxyethyl)amino)-2-propanol;(+/-)-1-((3-CHLORO-2-METHYLINDOL-4-YL)OXY)-3-((2-PHENOXYETHYL)AMINO)-2-PROPANOL

Chemical Property of Indopanolol

Chemical Property:

• Vapor Pressure: 3.41E-15mmHg at 25°C
• Boiling Point: 598.9°C at 760 mmHg
• Flash Point: 316°C
• PSA: 66.51000
• Density: 1.269
• LogP: 3.92890
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 374.1397203
• Heavy Atom Count: 26
• Complexity: 409

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C2=C(N1)C=CC=C2OCC(CNCCOC3=CC=CC=C3)O)Cl
• Uses: Indopanolol is a novel anti-inflammatory drug.

Technology Process of Indopanolol

There total 2 articles about Indopanolol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-4-(2,3-epoxypropoxy)-2-methylindole (62995-52-2) + phenoxyethylamine (76570-65-5) → (+/-)-1-[(3-chloro-2-methylindol-4-yl)oxy]-3-[(2-phenoxyethyl)amino]-2-propanol (69907-17-1)

Guidance literature:

In 1,4-dioxane;

Reference yield:

→ (+/-)-1-[(3-chloro-2-methylindol-4-yl)oxy]-3-[(2-phenoxyethyl)amino]-2-propanol (69907-17-1)

Guidance literature:

3-Chlor-4-(2,3-epoxypropoxy)-2-methyl-indol, Phenoxyethylamin;

upstream raw materials:

3-chloro-4-(2,3-epoxypropoxy)-2-methylindole

phenoxyethylamine