2-((2-hydroxy-1-naphthalenyl)methylene)-N-phenylhydrazinecarbothioamide

Base Information

• Chemical Name: 2-((2-hydroxy-1-naphthalenyl)methylene)-N-phenylhydrazinecarbothioamide
• CAS No.: 59157-24-3
• Molecular Formula: C18H15N3OS
• Molecular Weight: 321.403
• DSSTox Substance ID: DTXSID30974583
• Mol file: 59157-24-3.mol

Synonyms:SCHEMBL7261459;DTXSID30974583;2-((2-hydroxy-1-naphthalenyl)methylene)-N-phenylhydrazinecarbothioamide;2-[(2-Hydroxynaphthalen-1-yl)methylidene]-N-phenylhydrazine-1-carboximidothioic acid

Chemical Property of 2-((2-hydroxy-1-naphthalenyl)methylene)-N-phenylhydrazinecarbothioamide

Chemical Property:

• Vapor Pressure: 8.2E-11mmHg at 25°C
• Boiling Point: 517.4°Cat760mmHg
• Flash Point: 266.7°C
• Density: 1.399g/cm³
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 321.09358328
• Heavy Atom Count: 23
• Complexity: 423

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NC(=S)NN=CC2=C(C=CC3=CC=CC=C32)O

Technology Process of 2-((2-hydroxy-1-naphthalenyl)methylene)-N-phenylhydrazinecarbothioamide

There total 2 articles about 2-((2-hydroxy-1-naphthalenyl)methylene)-N-phenylhydrazinecarbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-Phenyl-3-thiosemicarbazide (5351-69-9) + 2-hydroxynaphthalene-1-carbaldehyde (708-06-5) → N-phenyl-2-(2-hydroxynaphthalen-1-ylmethylene)hydrazinecarbothioamide (59157-24-3)

Guidance literature:

In methanol; ethanol; at 20 ℃; for 28h;

DOI:10.1039/c5nj02429c

Reference yield: 70.0%

4-Phenyl-3-thiosemicarbazide (5351-69-9) + 2-hydroxynaphthalene-1-carbaldehyde (708-06-5) → 2-hydroxy-1-naphthilidene-phenylthiosemicarbazone (59157-24-3)

Guidance literature:

In ethanol; for 0.5h; Heating;

Reference yield: 97.29%

bis(acetylacetonato)dioxidomolybdenum(VI) + N-phenyl-2-(2-hydroxynaphthalen-1-ylmethylene)hydrazinecarbothioamide (59157-24-3) → [MoO2(OC10H6CHNNC(S)NHC6H5)]n

Guidance literature:

In acetonitrile; Mo compd. suspended in MeCN, ligand added, warmed for 6 h; filtered, washed with MeCN, dried; elem. anal.;

DOI:10.1002/zaac.200400495

upstream raw materials:

4-Phenyl-3-thiosemicarbazide

2-hydroxynaphthalene-1-carbaldehyde

Downstream raw materials:

[RuCl₂(dimethyl sulfoxide)2(2-hydroxy-1-naphthaldehyde 4-phenylthiosemicarbazone)]