2,2,3,3-Tetrafluoro-1,4-benzodioxane

Base Information

• Chemical Name: 2,2,3,3-Tetrafluoro-1,4-benzodioxane
• CAS No.: 94767-47-2
• Molecular Formula: C₈H₄F₄O₂
• Molecular Weight: 208.112
• Hs Code.: 2932990090
• European Community (EC) Number: 671-896-4
• DSSTox Substance ID: DTXSID30380206
• Wikidata: Q82170326
• Mol file: 94767-47-2.mol

Synonyms:94767-47-2;2,2,3,3-tetrafluoro-1,4-benzodioxane;2,2,3,3-tetrafluoro-1,4-benzodioxine;2,2,3,3-tetrafluorobenzodioxene;2,2,3,3-tetrafluoro-2,3-dihydro-1,4-benzodioxine;2,2,3,3-Tetrafluorobenzodioxane;2,2,3,3-tetrafluoro-1,4-benzodioxan;2,2,3,3-tetrafluoro-1,4-benzodioxene;2,2,3,3-Tetrafluoro-2,3-dihydro-benzo[1,4]dioxine;2,2,3,3-Tetrafluoro-1,4-benzodioxene;2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxine;2,2,3,3-tetrafluorobenzo-1,4-dioxane;SCHEMBL848935;DTXSID30380206;MFCD00236308;AKOS024318903;PS-11342;CS-0257462;FT-0609075;E72291;EN300-6731457;2,2,3,3-tetrafluoro-2,3-dihydro-1,4-benzodioxin;1,4-Benzodioxin,2,2,3,3-tetrafluoro-2,3-dihydro-;2,2,3,3-tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxine

Chemical Property of 2,2,3,3-Tetrafluoro-1,4-benzodioxane

Chemical Property:

• Vapor Pressure: 4.39mmHg at 25°C
• Refractive Index: 1.4206
• Boiling Point: 152.8 °C at 760 mmHg
• Flash Point: 52.2 °C
• PSA: 18.46000
• Density: 1.5 g/cm³
• LogP: 2.64340
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 208.01474201
• Heavy Atom Count: 14
• Complexity: 207

Purity/Quality:

97% ^*data from raw suppliers

2,2,3,3-Tetrafluoro-1,4-benzodioxane 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)OC(C(O2)(F)F)(F)F

Technology Process of 2,2,3,3-Tetrafluoro-1,4-benzodioxane

There total 4 articles about 2,2,3,3-Tetrafluoro-1,4-benzodioxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

o-(2-bromo-tetrafluoroethoxy)-phenol (220004-16-0) → 2,2,3,3-tetrafluoro-2,3-dihydro-1,4-benzodioxin (94767-47-2)

Guidance literature:

With potassium hydroxide; In sulfolane; methanol; toluene;

Reference yield:

o-(2-bromo-tetrafluoroethoxy)-phenol (220004-16-0) + potassium methanolate (865-33-8) → 2,2,3,3-tetrafluoro-2,3-dihydro-1,4-benzodioxin (94767-47-2)

Guidance literature:

In sulfolane; methanol; diethyl ether;

Reference yield:

6-bromo-2,2,3,3-tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin (141872-90-4) → 2,2,3,3-tetrafluoro-2,3-dihydro-1,4-benzodioxin (94767-47-2)

Guidance literature:

upstream raw materials:

o-(2-bromo-tetrafluoroethoxy)-phenol

potassium methanolate

6-bromo-2,2,3,3-tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin