2-Bromo-N-heptylacetamide

Base Information

• Chemical Name: 2-Bromo-N-heptylacetamide
• CAS No.: 5463-16-1
• Molecular Formula: C9H18BrNO
• Molecular Weight: 236.1493
• Hs Code.: 2924199090
• Mol file: 5463-16-1.mol

Synonyms:N-Heptyl-bromcetamid;N-heptylbromoacetamide;bromo-acetic acid heptylamide;Brom-essigsaeure-heptylamid;

Chemical Property of 2-Bromo-N-heptylacetamide

Chemical Property:

• Vapor Pressure: 0.000222mmHg at 25°C
• Boiling Point: 326°Cat760mmHg
• Flash Point: 150.9°C
• PSA: 29.10000
• Density: 1.203g/cm³
• LogP: 2.85880

Purity/Quality:

98%min ^*data from raw suppliers

2-Bromo-N-heptylacetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Bromo-N-heptylacetamide

There total 2 articles about 2-Bromo-N-heptylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-Heptylamine (111-68-2) + 2-Bromoacetyl bromide (598-21-0) → 2-bromo-N-heptylacetamide (5463-16-1)

Guidance literature:

With potassium carbonate; In dichloromethane; water; at 0 - 20 ℃; for 6.5h;

DOI:10.1039/c9cc00857h

Reference yield:

→ 2-bromo-N-heptylacetamide (5463-16-1)

Guidance literature:

With potassium carbonate; In dichloromethane; water; at 20 ℃; for 6h; Cooling with ice;

Reference yield:

2-bromo-N-heptylacetamide (5463-16-1) → 2-<(4,5-diphenyl-1H-imidazol-2-yl)thio>-N-heptyl-1-ethylamine (161669-65-4)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃, NaI / tetrahydrofuran

2: Red-Al / tetrahydrofuran / Heating

With potassium carbonate; sodium bis(2-methoxyethoxy)aluminium dihydride; sodium iodide; In tetrahydrofuran;

DOI:10.1021/jm00047a009

upstream raw materials:

1-Heptylamine

2-Bromoacetyl bromide

Downstream raw materials:

2-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-N-heptyl-acetamide

2-<(4,5-diphenyl-1H-imidazol-2-yl)thio>-N-heptyl-1-ethylamine

2-{1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl}-N-heptylacetamide