(4-Chlorobenzyl)propargyl ether

Base Information

Chemical Name:(4-Chlorobenzyl)propargyl ether
CAS No.:4039-86-5
Molecular Formula:C10H9ClO
Molecular Weight:180.634
Hs Code.:
European Community (EC) Number:813-130-5
DSSTox Substance ID:DTXSID201036266
Nikkaji Number:J3.503.979A
Mol file:4039-86-5.mol

Synonyms:(4-Chlorobenzyl)propargyl ether;SCHEMBL11861626;DTXSID201036266;4039-86-5;J3.503.979A;1-Chloro-4-[(2-propyn-1-yloxy)methyl]benzene

Suppliers and Price of (4-Chlorobenzyl)propargyl ether

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (4-Chlorobenzyl)propargyl ether

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:180.0341926
Heavy Atom Count:12
Complexity:162

Purity/Quality:: 99.9% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C#CCOCC1=CC=C(C=C1)Cl

Technology Process of (4-Chlorobenzyl)propargyl ether

There total 7 articles about (4-Chlorobenzyl)propargyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 14289-63-5
1-chloro-4-(2-propenyloxymethyl)benzene

: 4039-86-5
1-chloro-4-((prop-2-yn-1-yloxy)methyl)benzene

Guidance literature:: 1-chloro-4-(2-propenyloxymethyl)benzene; With pyridinium perbromide hydrobromide; In acetonitrile; at 20 ℃; for 12h; Molecular sieve; Inert atmosphere;

With tetra(n-butyl)ammonium hydroxide; dimethyl sulfoxide; triethylamine; In water; acetonitrile; at 0 - 60 ℃; for 2h; Reagent/catalyst; Molecular sieve; Inert atmosphere;
DOI:10.1055/s-0034-1380499

Reference yield: 95.0%

: 106-96-7
propargyl bromide

: 873-76-7
para-Chlorobenzyl alcohol

: 4039-86-5
1-chloro-4-((prop-2-yn-1-yloxy)methyl)benzene

Guidance literature:: With sodium hydride; In methanol; N,N-dimethyl-formamide; toluene; mineral oil; at 0 - 20 ℃;
DOI:10.1021/jm4010434

Reference yield: 95.0%

: 1236063-58-3
1-(2-bromoallyloxymethyl)-4-chlorobenzene

: 4039-86-5
1-chloro-4-((prop-2-yn-1-yloxy)methyl)benzene

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; N,N-dimethyl-formamide; at 60 ℃; for 1h; regioselective reaction;
DOI:10.1055/s-0030-1258813