Technology Process of darendoside B
There total 6 articles about darendoside B which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
methanol;
at 20 ℃;
Schlenk technique;
DOI:10.1080/07328303.2018.1541997
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 2,6-di-tert-butyl-4-methylpyridine / dichloromethane / 0.25 h / -40 °C / Molecular sieve
1.2: 0.05 h / -40 °C / Molecular sieve
1.3: 1 h / -40 °C / Molecular sieve
2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1 h / -20 °C
3.1: 2,6-di-tert-butyl-4-methylpyridine / dichloromethane / 0.17 h / 0 °C / Molecular sieve
3.2: 0.5 h / 0 °C / Molecular sieve
4.1: DL-dithiothreitol; camphor-10-sulfonic acid / dichloromethane / 8 h / 20 °C
5.1: sodium methylate / methanol / 96 h / 50 °C
6.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / Schlenk technique
With
2,6-di-tert-butyl-4-methylpyridine; DL-dithiothreitol; palladium 10% on activated carbon; camphor-10-sulfonic acid; hydrogen; sodium methylate; 3-chloro-benzenecarboperoxoic acid;
In
methanol; dichloromethane;
DOI:10.1080/07328303.2018.1541997
