cholest-4-en-3-ol

Base Information

• Chemical Name: cholest-4-en-3-ol
• CAS No.: 14597-42-3
• Molecular Formula: C₂₇H₄₆O
• Molecular Weight: 386.662
• Mol file: 14597-42-3.mol

Synonyms:NSC 224421

Chemical Property of cholest-4-en-3-ol

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 481.917°C at 760 mmHg
• Flash Point: 209.657°C
• Density: 0.988g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of cholest-4-en-3-ol

There total 15 articles about cholest-4-en-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Cholest-4-en-3-one (601-57-0) → 4-cholestene-3-ol (517-10-2,566-90-5,14597-42-3)

Guidance literature:

With hydrogen; H-β zeolite; iridium; In isopropyl alcohol; at 25 ℃; for 0.67h; under 21001.7 Torr;

DOI:10.1002/anie.200352275

Reference yield:

cholest-4-ene (16732-86-8) → Cholest-4-en-3-one (601-57-0) + 4-cholestene-3-ol (517-10-2,566-90-5,14597-42-3) + (4,5)α-epoxy-5α-cholestan (6079-19-2) + 4β,5β-epoxycholestane-3-one (23044-74-8)

Guidance literature:

With ammonium acetate; dihydrogen peroxide; Mn(III)-porphyrin derivative; In dichloromethane; acetonitrile; at 20 ℃; for 1h; Further byproducts given;

DOI:10.1002/ejoc.200400461

Reference yield:

Cholest-4-en-3-one (601-57-0) → 5α-cholestan-3α/β-ol (16720-60-8) + 4-cholestene-3-ol (517-10-2,566-90-5,14597-42-3)

Guidance literature:

With hydrogen; Dimethyl(phenyl)phosphine; tert-butyl alcohol; (triphenylphosphine)copper(I) hydride hexamer; In benzene; at 20 ℃; for 22h; under 10343 Torr;

DOI:10.1016/S0040-4020(00)00133-2

upstream raw materials:

Cholest-4-en-3-one

cholest-4-ene

Downstream raw materials:

Δ₄-cholesten-3-one

5α-cholestan-3-one

5β-cholestan-3-one

C₄₄H₆₂N₂O₂S