5-BROMO-1-(4-CHLOROBENZYL)-1H-INDOLE-3-CARBALDEHYDE

Base Information

Chemical Name:5-BROMO-1-(4-CHLOROBENZYL)-1H-INDOLE-3-CARBALDEHYDE
CAS No.:405274-93-3
Molecular Formula:C16H11BrClNO
Molecular Weight:348.626
Hs Code.:
Mol file:405274-93-3.mol

Synonyms:5-Bromo-1-(4-chloro-benzyl)-1H-indole-3-carbaldehyde;5-bromo-1-(4-chlorobenzyl)-3-formyl-1H-indole;

Suppliers and Price of 5-BROMO-1-(4-CHLOROBENZYL)-1H-INDOLE-3-CARBALDEHYDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-BROMO-1-(4-CHLOROBENZYL)-1H-INDOLE-3-CARBALDEHYDE

Chemical Property:

PSA：22.00000
LogP:4.91800

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-BROMO-1-(4-CHLOROBENZYL)-1H-INDOLE-3-CARBALDEHYDE

There total 5 articles about 5-BROMO-1-(4-CHLOROBENZYL)-1H-INDOLE-3-CARBALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 877-03-2
5-bromo-1H-indole-3-carboxaldehyde

: 104-83-6
1-Chloro-4-(chloromethyl)benzene

: 405274-93-3
5-bromo-1-(4-chlorobenzyl)-indole-3-carboxaldehyde

Guidance literature:: With sodium hydride; In dimethyl sulfoxide; at 20 ℃; for 2h;
DOI:10.1016/S0223-5234(02)00005-3

Reference yield:

: 877-03-2
5-bromo-1H-indole-3-carboxaldehyde

: 405274-93-3
5-bromo-1-(4-chlorobenzyl)-indole-3-carboxaldehyde

Guidance literature:: 5-bromo-1H-indole-3-carboxaldehyde; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.333333h; Inert atmosphere;

1-chloro-3-(halomethyl)benzene; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.5h; Inert atmosphere;
DOI:10.1016/j.bmcl.2018.01.017

Reference yield:

: 676590-33-3
5-bromo-1-(4-chlorobenzyl)-1H-indole

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 405274-93-3
5-bromo-1-(4-chlorobenzyl)-indole-3-carboxaldehyde

Guidance literature:: N,N-dimethyl-formamide; With trichlorophosphate; for 0.5h;

5-bromo-1-(4-chlorobenzyl)-1H-indole; at 20 ℃; for 1h;
DOI:10.1016/j.ejmech.2017.04.078