NICOTINIC ACID-CARBOXY-14C

Base Information

• Chemical Name: NICOTINIC ACID-CARBOXY-14C
• CAS No.: 2906-42-5
• Molecular Formula: C₆H₅NO₂
• Molecular Weight: 125.1
• Mol file: 2906-42-5.mol

Synonyms:Nicotinic-carboxy-14Cacid (6CI,7CI)

Chemical Property of NICOTINIC ACID-CARBOXY-14C

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 50.19000
• Density: 1.293g/cm³
• LogP: 0.77980
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

NICOTINIC ACID[CARBOXYL-14C] 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of NICOTINIC ACID-CARBOXY-14C

There total 3 articles about NICOTINIC ACID-CARBOXY-14C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

3-Bromopyridine (626-55-1,163928-56-1) + [14C]carbon dioxide (51-90-1) → [1-14C]-nicotinic acid (2906-42-5)

Guidance literature:

3-Bromopyridine; With n-butyllithium; In diethyl ether; at -70 ℃; for 1.16667h;

[14C]carbon dioxide; at -70 ℃; Cooling with liquid nitrogen;

DOI:10.1002/jlcr.3186

Reference yield:

[carboxyl-14C]nicotinate riboside → [1-14C]-nicotinic acid (2906-42-5)

Guidance literature:

With HEPES-NaOH buffer; ATP; magnesium chloride; nicotinate riboside nucleosidase; at 30 ℃; pH=7.6;

DOI:10.1016/j.phytochem.2007.08.008

Reference yield:

→ [1-14C]-nicotinic acid (2906-42-5)

Guidance literature:

DOI:10.1002/hlca.19690520134 DOI:10.1002/jlcr.2580150142 DOI:10.1016/0031-9422(74)85101-0

upstream raw materials:

3-Bromopyridine

[14C]carbon dioxide

Refernces

• 1、 Zheng, Xin-Qiang,Matsui, Ayu,Ashihara, Hiroshi. "Biosynthesis of trigonelline from nicotinate mononucleotide in mungbean seedlings". . p. 390 - 395. Retrieved 2008.