[6aS,(-)]-8β-Chloro-9α-ethenyl-2,6,6aα,7,8,9,10,10aβ-octahydro-10α-isocyano-6,6,9-trimethylnaphtho[1,2,3-cd]indole

Base Information

Chemical Name:[6aS,(-)]-8β-Chloro-9α-ethenyl-2,6,6aα,7,8,9,10,10aβ-octahydro-10α-isocyano-6,6,9-trimethylnaphtho[1,2,3-cd]indole
CAS No.:102045-13-6
Molecular Formula:C₂₁H₂₃ClN₂
Molecular Weight:338.88
Hs Code.:
Mol file:102045-13-6.mol

Synonyms:Naphth[1,2,3-cd]indole,8-chloro-9-ethenyl-2,6,6a,7,8,9,10,10a-octahydro-10-isocyano-6,6,9-trimethyl-,[6aS-(6aa,8b,9a,10a,10ab)]-; (-)-Hapalindole G; Hapalindole G

Suppliers and Price of [6aS,(-)]-8β-Chloro-9α-ethenyl-2,6,6aα,7,8,9,10,10aβ-octahydro-10α-isocyano-6,6,9-trimethylnaphtho[1,2,3-cd]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 2 raw suppliers

Chemical Property of [6aS,(-)]-8β-Chloro-9α-ethenyl-2,6,6aα,7,8,9,10,10aβ-octahydro-10α-isocyano-6,6,9-trimethylnaphtho[1,2,3-cd]indole

Chemical Property:

PSA：28.15000
LogP:5.18550

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of [6aS,(-)]-8β-Chloro-9α-ethenyl-2,6,6aα,7,8,9,10,10aβ-octahydro-10α-isocyano-6,6,9-trimethylnaphtho[1,2,3-cd]indole

There total 20 articles about [6aS,(-)]-8β-Chloro-9α-ethenyl-2,6,6aα,7,8,9,10,10aβ-octahydro-10α-isocyano-6,6,9-trimethylnaphtho[1,2,3-cd]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 117249-41-9
N-((6aS,8R,9R,10R,10aS)-8-Chloro-6,6,9-trimethyl-9-vinyl-2,6,6a,7,8,9,10,10a-octahydro-2-aza-aceanthrylen-10-yl)-formamide

: 102045-13-6
(-)-hapalindole G

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃;
DOI:10.1021/ja00086a053

Reference yield:

: 92219-95-9
hapalindole A

: 106865-63-8
hapalindole K

: 102045-13-6
(-)-hapalindole G

: 101968-76-7
hapalindole I

: 109217-18-7
10-methoxyhapalindole

Guidance literature:: With oxygen; rose bengal; In methanol; at 25 ℃; for 5h; Further byproducts given; Irradiation;
DOI:10.1021/jo00226a009

Reference yield:

: 117249-42-0
(6aS,8R,9R,10R,10aS)-8-Chloro-6,6,9-trimethyl-9-vinyl-2,6,6a,7,8,9,10,10a-octahydro-2-aza-aceanthrylen-10-ylamine

: 102045-13-6
(-)-hapalindole G

Guidance literature:: Multi-step reaction with 2 steps

1: Ac₂O, pyridine / CH₂Cl₂ / 23 °C

2: 90 percent / COCl₂, Et₃N / CH₂Cl₂ / 0 °C

With pyridine; acetic anhydride; triethylamine; In dichloromethane;
DOI:10.1021/ja00086a053