Dimethyl (2-oxo-3-(m-tolyloxy)propyl)phosphonate

Base Information

Chemical Name:Dimethyl (2-oxo-3-(m-tolyloxy)propyl)phosphonate
CAS No.:40666-12-4
Molecular Formula:C₁₂H₁₇O₅P
Molecular Weight:272.238
Hs Code.:
DSSTox Substance ID:DTXSID40574851
Wikidata:Q82464025
Mol file:40666-12-4.mol

Synonyms:40666-12-4;Dimethyl (2-oxo-3-(m-tolyloxy)propyl)phosphonate;SCHEMBL11822728;DTXSID40574851;Dimethyl(2-oxo-3-(m-tolyloxy)propyl)phosphonate;Dimethyl [3-(3-methylphenoxy)-2-oxopropyl]phosphonate

Suppliers and Price of Dimethyl (2-oxo-3-(m-tolyloxy)propyl)phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Dimethyl (2-oxo-3-(m-tolyloxy)propyl)phosphonate

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:272.08136064
Heavy Atom Count:18
Complexity:310

Purity/Quality:: 95+% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC=C1)OCC(=O)CP(=O)(OC)OC

Technology Process of Dimethyl (2-oxo-3-(m-tolyloxy)propyl)phosphonate

There total 1 articles about Dimethyl (2-oxo-3-(m-tolyloxy)propyl)phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 40666-12-4
dimethyl 2-oxo-3-(m-methylphenoxy)propylphosphonate

Guidance literature:: Dimethyl-methylphosphonat, n-BuLi, Me-2-m-tolyloxyacetat;

Reference yield:

: 40666-12-4
dimethyl 2-oxo-3-(m-methylphenoxy)propylphosphonate

: (3aR,4R,5R,6aS)-5-Hydroxy-4-((E)-(R)-3-hydroxy-4-m-tolyloxy-but-1-enyl)-hexahydro-cyclopenta[b]furan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaH / 1.) THF, 90 min, 2.) THF, 30 min

2: lithium triethylborohydride / tetrahydrofuran / 0.5 h

3: potassium carbonate / methanol; tetrahydrofuran / 2.5 h

With sodium hydride; lithium triethylborohydride; potassium carbonate; In tetrahydrofuran; methanol;
DOI:10.1021/jm00143a018

Reference yield:

: 40666-12-4
dimethyl 2-oxo-3-(m-methylphenoxy)propylphosphonate

: 79124-53-1
(3aR,4R,5R,6aS)-5-(Tetrahydro-pyran-2-yloxy)-4-[(E)-(R)-3-(tetrahydro-pyran-2-yloxy)-4-m-tolyloxy-but-1-enyl]-hexahydro-cyclopenta[b]furan-2-ol

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) NaH / 1.) THF, 90 min, 2.) THF, 30 min

2: lithium triethylborohydride / tetrahydrofuran / 0.5 h

3: potassium carbonate / methanol; tetrahydrofuran / 2.5 h

4: p-toluenesulfonic acid / CH₂Cl₂ / 0.5 h

5: diisobutylaluminum hydride / toluene; hexane / 0.33 h

With sodium hydride; diisobutylaluminium hydride; lithium triethylborohydride; potassium carbonate; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; hexane; dichloromethane; toluene;
DOI:10.1021/jm00143a018