POLYMYXIN B NONAPEPTIDE HYDROCHLORIDE

Base Information

Chemical Name:POLYMYXIN B NONAPEPTIDE HYDROCHLORIDE
CAS No.:86408-36-8
Molecular Formula:C43H74N14O11
Molecular Weight:963.148
Hs Code.:
Nikkaji Number:J389.963B
ChEMBL ID:CHEMBL501248

Synonyms:H-Thr-2,4-diaminobutyryl-cyclo[2,4-diaminobutyryl-2,4-diaminobutyryl-D-Phe-Leu-2,4-diaminobutyryl-2,4-diaminobutyryl-Thr];polymyxin B nonapeptide;HSSi(i-Pr)3;polymixin B nonapeptide;T-X-cyclo[X-X-DF-L-X-X-T];TRI-ISOPROPYLSILANETHIOL;triisopropylsilanthiol;H-Thr-Dab-cyclic-(Dab-Dab-D-Phe-Leu-Dab-Dab-Thr);

Suppliers and Price of POLYMYXIN B NONAPEPTIDE HYDROCHLORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
PolymyxinBNonapeptide
5mg
$ 130.00

Sigma-Aldrich
Polymyxin B nonapeptide hydrochloride cationic cyclic peptide
5mg
$ 131.00

ChemScene
PolymyxinBnonapeptide 97.45%
10mg
$ 250.00

ChemScene
PolymyxinBnonapeptide 97.45%
5mg
$ 150.00

ChemScene
PolymyxinBnonapeptide 97.45%
100mg
$ 1650.00

ChemScene
PolymyxinBnonapeptide 97.45%
50mg
$ 950.00

American Custom Chemicals Corporation
POLYMYXIN B NONAPEPTIDE HYDROCHLORIDE 95.00%
5MG
$ 690.51

Total 20 raw suppliers

Chemical Property of POLYMYXIN B NONAPEPTIDE HYDROCHLORIDE

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:1456.2°Cat760mmHg
Flash Point:834.5°C
PSA：463.87000
Density:1.32g/cm³
LogP:0.27100
Storage Temp.:2-8°C
XLogP3:-4.8
Hydrogen Bond Donor Count:16
Hydrogen Bond Acceptor Count:16
Rotatable Bond Count:18
Exact Mass:962.56614923
Heavy Atom Count:68
Complexity:1690

Purity/Quality:

99%, ^*data from raw suppliers

PolymyxinBNonapeptide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(C)CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCCC(C(=O)NC(C(=O)NC(C(=O)N1)CC2=CC=CC=C2)CCN)NC(=O)C(CCN)NC(=O)C(C(C)O)N)C(C)O)CCN)CCN
Isomeric SMILES:C[C@H]([C@H]1C(=O)NCC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCN)CCN)CC(C)C)CC2=CC=CC=C2)CCN)NC(=O)[C@H](CCN)NC(=O)[C@H]([C@@H](C)O)N)O
Uses Polymyxin B Nonapeptide can be used in biological study of role of outer membrane and porins in susceptibility of β-lactamase-producing Enterobacteriaceae to ceftazidime-avibactam.

Technology Process of POLYMYXIN B NONAPEPTIDE HYDROCHLORIDE

There total 6 articles about POLYMYXIN B NONAPEPTIDE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4135-11-9
polymyxin B

: 86408-36-8
H-Thr-L-α,γ-diaminobutyryl-cyclo(L-α,γ-diaminobutyryl-L-α,γ-diaminobutyryl-D-Phe-Leu-L-α,γ-diaminobutyryl-L-α,γ-diaminobutyryl-Thr)

Guidance literature:: With papain;
DOI:10.1128/AAC.49.8.3122-3128.2005

Reference yield:

: C₈₃H₁₀₄N₁₄O₂₁

: 86408-36-8
H-Thr-L-α,γ-diaminobutyryl-cyclo(L-α,γ-diaminobutyryl-L-α,γ-diaminobutyryl-D-Phe-Leu-L-α,γ-diaminobutyryl-L-α,γ-diaminobutyryl-Thr)

Guidance literature:: With hydrogen; acetic acid; palladium on activated charcoal; In methanol;
DOI:10.1021/jm0000057

Reference yield:

: C₈₂H₁₂₃N₁₄O₂₁Pol

: 86408-36-8
H-Thr-L-α,γ-diaminobutyryl-cyclo(L-α,γ-diaminobutyryl-L-α,γ-diaminobutyryl-D-Phe-Leu-L-α,γ-diaminobutyryl-L-α,γ-diaminobutyryl-Thr)

Guidance literature:: C₈₂H₁₂₃N₁₄O₂₁Pol; With piperidine; In N,N-dimethyl-formamide;

With triethylsilane; water; trifluoroacetic acid; at 20 ℃; for 0.5h;
DOI:10.3390/molecules24030553