methyl 2-O-beta-rhamnopyranosyl-beta-galactopyranoside

Base Information

• Chemical Name: methyl 2-O-beta-rhamnopyranosyl-beta-galactopyranoside
• CAS No.: 128962-64-1
• Molecular Formula: C₁₃H₂₄O₁₀
• Molecular Weight: 340.328
• Mol file: 128962-64-1.mol

Synonyms:(2R,3R,4R,5R,6S)-2-((2R,3R,4S,5R,6R)-4,5-Dihydroxy-6-hydroxymethyl-2-methoxy-tetrahydro-pyran-3-yloxy)-6-methyl-tetrahydro-pyran-3,4,5-triol;

Chemical Property of methyl 2-O-beta-rhamnopyranosyl-beta-galactopyranoside

Chemical Property:

• Vapor Pressure: 2.75E-16mmHg at 25°C
• Boiling Point: 588.2°Cat760mmHg
• Flash Point: 309.6°C
• PSA: 158.30000
• Density: 1.53g/cm³
• LogP: -3.71550

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 2-O-beta-rhamnopyranosyl-beta-galactopyranoside

There total 6 articles about methyl 2-O-beta-rhamnopyranosyl-beta-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(2,3,4-tri-O-benzyl-β-L-rhamnopyranosyl)-β-D-galactopyranoside (129031-01-2) → methyl 2-O-β-L-rhamnopyranosyl-β-D-galactopyranoside (128962-64-1)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; for 20h; Ambient temperature;

DOI:10.1016/0008-6215(90)84132-E

Reference yield:

2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl bromide (59055-61-7) → methyl 2-O-β-L-rhamnopyranosyl-β-D-galactopyranoside (128962-64-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 46 percent / Ag₂CO₃, molecular sieve 4 Angstroem / CH₂Cl₂ / 20 h / Ambient temperature

2: 94 percent / H₂, 10percent Pd/C / methanol / 20 h / Ambient temperature

With palladium on activated charcoal; 4 A molecular sieve; hydrogen; silver carbonate; In methanol; dichloromethane;

DOI:10.1016/0008-6215(90)84132-E

Reference yield:

ethyl 2,3,4-tri-O-benzyl-1-thio-α-L-rhamanopyranoside (128962-63-0,116391-11-8) → methyl 2-O-β-L-rhamnopyranosyl-β-D-galactopyranoside (128962-64-1)

Guidance literature:

Multi-step reaction with 3 steps

1: bromine / CH₂Cl₂ / 0.25 h / 0 °C

2: 46 percent / Ag₂CO₃, molecular sieve 4 Angstroem / CH₂Cl₂ / 20 h / Ambient temperature

3: 94 percent / H₂, 10percent Pd/C / methanol / 20 h / Ambient temperature

With palladium on activated charcoal; 4 A molecular sieve; hydrogen; bromine; silver carbonate; In methanol; dichloromethane;

DOI:10.1016/0008-6215(90)84132-E

upstream raw materials:

methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(2,3,4-tri-O-benzyl-β-L-rhamnopyranosyl)-β-D-galactopyranoside

2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl bromide

ethyl 2,3,4-tri-O-benzyl-1-thio-α-L-rhamanopyranoside

methyl 3-O-benzyl-β-D-galactopyranoside