{4-[(But-2-en-1-yl)oxy]phenyl}(phenyl)methanone

Base Information

• Chemical Name: {4-[(But-2-en-1-yl)oxy]phenyl}(phenyl)methanone
• CAS No.: 42403-76-9
• Molecular Formula: C₁₇H₁₆O₂
• Molecular Weight: 252.313
• DSSTox Substance ID: DTXSID40707223
• Mol file: 42403-76-9.mol

Synonyms:42403-76-9;4-crotyloxybenzophenone;{4-[(But-2-en-1-yl)oxy]phenyl}(phenyl)methanone;DTXSID40707223;GYARYIXMCQUTFI-UHFFFAOYSA-N

Chemical Property of {4-[(But-2-en-1-yl)oxy]phenyl}(phenyl)methanone

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 252.115029749
• Heavy Atom Count: 19
• Complexity: 294

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC=CCOC1=CC=C(C=C1)C(=O)C2=CC=CC=C2

Technology Process of {4-[(But-2-en-1-yl)oxy]phenyl}(phenyl)methanone

There total 1 articles about {4-[(But-2-en-1-yl)oxy]phenyl}(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E/Z)-crotyl bromide (4784-77-4,29576-14-5,39616-19-8) + 4-Hydroxybenzophenone (1137-42-4) → 4-(crotyloxy)benzophenone (42403-76-9)

Guidance literature:

With potassium carbonate; sodium iodide; In acetone; for 96h; Heating;

DOI:10.1021/jm00400a030

Reference yield:

4-(crotyloxy)benzophenone (42403-76-9) → 3-(α-methallyl)-4-hydroxybenzophenone (73720-57-7)

Guidance literature:

With N,N-diethylaniline; at 207 - 218 ℃; for 3.5h;

DOI:10.1021/jm00400a030

Reference yield:

4-(crotyloxy)benzophenone (42403-76-9) → 2-(5-benzoyl-2-hydroxyphenyl)propionic acid (109217-30-3)

Guidance literature:

Multi-step reaction with 5 steps

1: diethylaniline / 3.5 h / 207 - 218 °C

2: 91 percent / pyridine / 2 h / 50 °C

3: 59 percent / NaIO₄, OsO₄ / ethanol; H₂O / 4 h / 25 °C

4: 50 percent / Jones' reagent / acetone / 0 °C

5: NaOH / methanol / 3 h / 50 °C

With pyridine; sodium hydroxide; sodium periodate; osmium(VIII) oxide; jones' reagent; N,N-diethylaniline; In methanol; ethanol; water; acetone;

DOI:10.1021/jm00400a030

upstream raw materials:

(E/Z)-crotyl bromide

4-Hydroxybenzophenone

Downstream raw materials:

3-(α-methallyl)-4-hydroxybenzophenone

2-oxo-3-methyl-5-benzoyl-2,3-dihydrobenzofuran

2-(5-benzoyl-2-hydroxyphenyl)propionic acid

3-(1-methallyl)-4-(pivaloyloxy)benzophenone