Undecanoic acid, 11-(4-ethynylphenoxy)-

Base Information

• Chemical Name: Undecanoic acid, 11-(4-ethynylphenoxy)-
• CAS No.: 426219-95-6
• Molecular Formula: C19H26O3
• Molecular Weight: 302.414
• Mol file: 426219-95-6.mol

Synonyms:

Chemical Property of Undecanoic acid, 11-(4-ethynylphenoxy)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Undecanoic acid, 11-(4-ethynylphenoxy)-

There total 4 articles about Undecanoic acid, 11-(4-ethynylphenoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.1%

methyl 11-[(4-trimethylsilylethynyl)phenoxy]undecanoate (372163-17-2) → 11-(4-ethynylphenoxy)undecanoic acid (426219-95-6)

Guidance literature:

With potassium hydroxide; In methanol; for 4h; Heating;

DOI:10.1021/ma0344543

Reference yield:

11-bromo-undecanoic acid methyl ester (6287-90-7) → 11-(4-ethynylphenoxy)undecanoic acid (426219-95-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 79.3 percent / potassium hydroxide; potassium iodide / acetone; dimethylsulfoxide / 24 h / Heating

2: 92.7 percent / triethylamine / bis(triphenylphosphine)palladium(II) chloride; copper(I) iodide / 12 h / 20 °C

3: 95.1 percent / potassium hydroxide / methanol / 4 h / Heating

With potassium hydroxide; triethylamine; potassium iodide; copper(l) iodide; bis(triphenylphosphine)palladium(II)-chloride; In methanol; dimethyl sulfoxide; acetone;

DOI:10.1039/b617595c

Reference yield:

11-bromoundecanoic acid (2834-05-1) → 11-(4-ethynylphenoxy)undecanoic acid (426219-95-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 85.2 percent / conc. sulfuric acid / 2 h / Heating

2: 79.3 percent / potassium hydroxide; potassium iodide / acetone; dimethylsulfoxide / 24 h / Heating

3: 92.7 percent / triethylamine / bis(triphenylphosphine)palladium(II) chloride; copper(I) iodide / 12 h / 20 °C

4: 95.1 percent / potassium hydroxide / methanol / 4 h / Heating

With potassium hydroxide; sulfuric acid; triethylamine; potassium iodide; copper(l) iodide; bis(triphenylphosphine)palladium(II)-chloride; In methanol; dimethyl sulfoxide; acetone;

DOI:10.1039/b617595c

upstream raw materials:

methyl 11-[(4-trimethylsilylethynyl)phenoxy]undecanoate

11-bromoundecanoic acid

11-bromo-undecanoic acid methyl ester

methyl 11-(4-iodophenoxy)undecanoate

Downstream raw materials:

(C₅H₅)Fe(C₅H₄C(O)O(CH₂)4OC(O)(CH₂)10OC₆H₄CCH)

perfluorophenyl 11-(4-ethynylphenoxy)undecanoate

11-(4-ethynylphenoxy)undecanoyl-L-leucine methyl ester