N-(4-bromo-2-methylphenyl)-2-naphthamide

Base Information

• Chemical Name: N-(4-bromo-2-methylphenyl)-2-naphthamide
• CAS No.: 429627-41-8
• Molecular Formula: C18H14BrNO
• Molecular Weight: 340.21400
• UNII: 3W4NVD97ZD
• DSSTox Substance ID: DTXSID40356417
• Wikidata: Q82135737
• ChEMBL ID: CHEMBL217951
• Mol file: 429627-41-8.mol

Synonyms:N-(4-bromo-2-methylphenyl)naphthalene-2-carboxamide;N-(4-bromo-2-methylphenyl)-2-naphthamide;429627-41-8;3W4NVD97ZD;UNII-3W4NVD97ZD;2-Naphthalenecarboxamide, N-(4-bromo-2-methylphenyl)-;N-(4-Bromo-2-methylphenyl)-2-naphthalenecarboxamide;N-(4-Bromanyl-2-methyl-phenyl)naphthalene-2-carboxamide;Naphthalene-2-carboxylic acid (4-bromo-2-methyl-phenyl)-amide;naphthamide compound 2;ChemBridge compound no. 2;CHEMBL217951;BDBM14710;DTXSID40356417;STK222653;AKOS000202277;PD186891;AG-670/40742092

Chemical Property of N-(4-bromo-2-methylphenyl)-2-naphthamide

Chemical Property:

• PSA: 29.10000
• LogP: 5.23600
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 339.02588
• Heavy Atom Count: 21
• Complexity: 372

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1)Br)NC(=O)C2=CC3=CC=CC=C3C=C2

Technology Process of N-(4-bromo-2-methylphenyl)-2-naphthamide

There total 1 articles about N-(4-bromo-2-methylphenyl)-2-naphthamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

4-Bromo-2-methylaniline (583-75-5) + 2-naphthaloyl chloride (2243-83-6) → naphthalene-2-carboxylic acid (4-bromo-2-methyl-phenyl)-amide (429627-41-8)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1021/jm060687j

upstream raw materials:

4-Bromo-2-methylaniline

2-naphthaloyl chloride