Benzene, 1,2,3-tris[[(3S)-3,7-dimethyloctyl]oxy]-5-ethynyl-

Base Information

• Chemical Name: Benzene, 1,2,3-tris[[(3S)-3,7-dimethyloctyl]oxy]-5-ethynyl-
• CAS No.: 437762-55-5
• Molecular Formula: C38H66O3
• Molecular Weight: 570.94
• Mol file: 437762-55-5.mol

Synonyms:

Chemical Property of Benzene, 1,2,3-tris[[(3S)-3,7-dimethyloctyl]oxy]-5-ethynyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzene, 1,2,3-tris[[(3S)-3,7-dimethyloctyl]oxy]-5-ethynyl-

There total 6 articles about Benzene, 1,2,3-tris[[(3S)-3,7-dimethyloctyl]oxy]-5-ethynyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

3,4,5-tris((S)-3,7-dimethyloctan-1-yloxy)-(2-trimethylsilyl)ethynylbenzene (921229-82-5) → 3,4,5-tris((S)-3,7-dimethyloctan-1-yloxy)phenylacetylene (437762-55-5)

Guidance literature:

With methanol; potassium carbonate; In tetrahydrofuran; at 23 ℃; for 3h;

DOI:10.1021/ja0665848

Reference yield:

1,2,3-tris((S)-3,7-dimethyloctan-1-yloxy)benzene (921229-75-6) → 3,4,5-tris((S)-3,7-dimethyloctan-1-yloxy)phenylacetylene (437762-55-5)

Guidance literature:

Multi-step reaction with 6 steps

1: 86 percent / silica gel-supported nitric acid / CH₂Cl₂ / 0.08 h

2: 94 percent / hydrazine monohydrate; graphite / ethanol / 12 h / Heating

3: 90 percent / aq. HBF₄; t-butyl nitrite / CH₂Cl₂; tetrahydrofuran / 10 - 15 °C

4: 90 percent / potassium acetate; 18-crown-6; I₂ / CHCl₃

5: 90 percent / NEt₃; CuI / bis(triphenylphosphine)palladium(II)dichloride

6: 85 percent / K₂CO₃; MeOH / tetrahydrofuran / 3 h / 23 °C

With methanol; copper(l) iodide; tetrafluoroboric acid; tert.-butylnitrite; 18-crown-6 ether; iodine; nitric acid; potassium acetate; silica gel; potassium carbonate; pyrographite; hydrazine hydrate; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; ethanol; dichloromethane; chloroform;

DOI:10.1021/ja0665848

Reference yield:

3,4,5-tris((S)-3,7-dimethyloctan-1-yloxy)benzenediazonium tetrafluoroborate → 3,4,5-tris((S)-3,7-dimethyloctan-1-yloxy)phenylacetylene (437762-55-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 90 percent / potassium acetate; 18-crown-6; I₂ / CHCl₃

2: 90 percent / NEt₃; CuI / bis(triphenylphosphine)palladium(II)dichloride

3: 85 percent / K₂CO₃; MeOH / tetrahydrofuran / 3 h / 23 °C

With methanol; copper(l) iodide; 18-crown-6 ether; iodine; potassium acetate; potassium carbonate; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; chloroform;

DOI:10.1021/ja0665848

upstream raw materials:

3,4,5-tris((S)-3,7-dimethyloctan-1-yloxy)-(2-trimethylsilyl)ethynylbenzene

1,2,3-tris((S)-3,7-dimethyloctan-1-yloxy)benzene

(S)-1-bromo-3,7-dimethyloctane

2-hydroxyresorcinol