2-Amino-1-phenylethane-1-sulfonic acid

Base Information

Chemical Name:2-Amino-1-phenylethane-1-sulfonic acid
CAS No.:4430-27-7
Molecular Formula:C8H11NO3S
Molecular Weight:201.246
Hs Code.:
European Community (EC) Number:859-879-1
Nikkaji Number:J2.222.260K
Mol file:4430-27-7.mol

Synonyms:4430-27-7;SCHEMBL1663424;2-amino-1-phenylethane-1-sulfonic acid;EN300-8227533;Z1509515000

Suppliers and Price of 2-Amino-1-phenylethane-1-sulfonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Amino-1-phenylethane-1-sulfonic acid

Chemical Property:

XLogP3:-2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:201.04596439
Heavy Atom Count:13
Complexity:239

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(CN)S(=O)(=O)O

Technology Process of 2-Amino-1-phenylethane-1-sulfonic acid

There total 10 articles about 2-Amino-1-phenylethane-1-sulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 678166-60-4
2-(benzyloxycarbonyl)amino-1-phenylethyl thioacetate

: 4430-27-7
2-amino-1-phenylethane-1-sulfonic acid

Guidance literature:: With formic acid; dihydrogen peroxide; Heating;
DOI:10.1055/s-2003-44382

Reference yield:

: 1498-99-3
styrenesulfide

: 103-49-1
dibenzylamine

: 97272-96-3
2-amino-2-phenylethanesulfonic acid

: 4430-27-7
2-amino-1-phenylethane-1-sulfonic acid

Guidance literature:: styrenesulfide; dibenzylamine; In ethanol; benzene; at 60 ℃; for 24h;

With hydrogenchloride; formic acid; dihydrogen peroxide; at 0 - 20 ℃; for 50h;

With hydrogen; palladium dihydroxide; In methanol; at 50 ℃; Title compound not separated from byproducts;
DOI:10.1055/s-2005-869994

Reference yield:

: 100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6
styrene

: 4430-27-7
2-amino-1-phenylethane-1-sulfonic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 63 percent / Oxone; dichloroacetone

2: NH₃*H₂O / ethanol / 20 °C

3: aq. NaOH / CH₂Cl₂ / 20 °C

4: 63 percent / diethyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 21 h / -10 - 20 °C

5: 90 percent / aq. H₂O₂; HCO₂H / Heating

With Oxone; sodium hydroxide; formic acid; 1,1-Dichloroacetone; ammonia; dihydrogen peroxide; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1055/s-2003-44382