1,2,4-Triazine-5-carbonitrile, 6-phenyl-3-(2-pyridinyl)-

Base Information

Chemical Name:1,2,4-Triazine-5-carbonitrile, 6-phenyl-3-(2-pyridinyl)-
CAS No.:453556-96-2
Molecular Formula:C15H9N5
Molecular Weight:259.27
Hs Code.:
DSSTox Substance ID:DTXSID50455142
Nikkaji Number:J1.891.385B

Synonyms:1,2,4-Triazine-5-carbonitrile, 6-phenyl-3-(2-pyridinyl)-;453556-96-2;6-Phenyl-3-(2-pyridyl)-1,2,4-triazine-5-carbonitrile;DTXSID50455142

Suppliers and Price of 1,2,4-Triazine-5-carbonitrile, 6-phenyl-3-(2-pyridinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 1,2,4-Triazine-5-carbonitrile, 6-phenyl-3-(2-pyridinyl)-

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:259.08579531
Heavy Atom Count:20
Complexity:357

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(N=C(N=N2)C3=CC=CC=N3)C#N

Technology Process of 1,2,4-Triazine-5-carbonitrile, 6-phenyl-3-(2-pyridinyl)-

There total 6 articles about 1,2,4-Triazine-5-carbonitrile, 6-phenyl-3-(2-pyridinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 75-86-5
2-hydroxy-2-methylpropanenitrile

: 453556-95-1
6-phenyl-3-(2'-pyridyl)-1,2,4-triazine-4-oxide

: 453556-96-2
6-phenyl-3-(pyridin-2-yl)-1,2,4-triazine-5-carbonitrile

Guidance literature:: With triethylamine; In dichloromethane; for 0.5h; Heating;

Reference yield: 30.0%

: C₂₃H₁₅F₃N₄O

: 453556-96-2
6-phenyl-3-(pyridin-2-yl)-1,2,4-triazine-5-carbonitrile

Guidance literature:: With benzoic acid; isopentyl nitrite; In 1,4-dioxane; toluene; for 1.5h; Reflux;
DOI:10.1055/s-0036-1590961

Reference yield:

: (1E,2Z)-2-hydrazono-2-phenylacetaldehyde oxime

: 453556-96-2
6-phenyl-3-(pyridin-2-yl)-1,2,4-triazine-5-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / ethanol / 12 h / 20 °C

2: 54 percent / Pb₃O₄; acetic acid / 4 h / 20 °C

3: 75 percent / triethylamine / CH₂Cl₂ / 1 h / Heating

With lead(II,IV) oxide; acetic acid; triethylamine; In ethanol; dichloromethane;
DOI:10.1021/jo0267955