Spiro[3.5]non-2-en-1-one, 3-ethoxy-7-methoxy- (9CI)

Base Information

Chemical Name:Spiro[3.5]non-2-en-1-one, 3-ethoxy-7-methoxy- (9CI)
CAS No.:455264-58-1
Molecular Formula:C₁₂H₁₈O₃
Molecular Weight:210.273
Hs Code.:
Mol file:455264-58-1.mol

Synonyms:3-ethoxy-7-diethylamino-2H-benzopyran-2-one;2H-1-Benzopyran-2-one,7-(diethylamino)-4-ethoxy;

Suppliers and Price of Spiro[3.5]non-2-en-1-one, 3-ethoxy-7-methoxy- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Spiro[3.5]non-2-en-1-one, 3-ethoxy-7-methoxy- (9CI)

Chemical Property:

PSA：35.53000
LogP:2.06490

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Spiro[3.5]non-2-en-1-one, 3-ethoxy-7-methoxy- (9CI)

There total 1 articles about Spiro[3.5]non-2-en-1-one, 3-ethoxy-7-methoxy- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 123790-13-6
4-methoxycyclohexanecarbonyl chloride

: 927-80-0
1-ethoxyacetylene

: 455264-58-1
3-ethoxy-7-methoxyspiro[3.5]non-2-en-1-one

Guidance literature:: With triethylamine; In diethyl ether; hexane; for 576h; Heating;
DOI:10.1021/ol034701n

Reference yield:

: 455264-58-1
3-ethoxy-7-methoxyspiro[3.5]non-2-en-1-one

: ethyl (2S)-2-[(7-methoxy-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-{4-[(3,5-dichloroisonicotinoyl)amino]phenyl}propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / hydrochloric acid / H₂O / 18 h / 20 °C

2: 87 percent / tetrahydrofuran / 20 °C

With hydrogenchloride; In tetrahydrofuran; water;
DOI:10.1021/ol034701n