N,N-Dimethyl-4H-thieno(3,2-b)(1)benzazepine-4-propanamine (E)-2-butenedioate (1:1)

Base Information

Chemical Name:N,N-Dimethyl-4H-thieno(3,2-b)(1)benzazepine-4-propanamine (E)-2-butenedioate (1:1)
CAS No.:37967-99-0
Molecular Formula:C21H24N2O4S
Molecular Weight:400.4913
Hs Code.:

Synonyms:N,N-Dimethyl-4H-thieno(3,2-b)(1)benzazepine-4-propanamine (E)-2-butenedioate (1:1);4-(gamma-Dimethylaminopropyl)-(4H)-thieno-(3,2-b)(f)-benzazepine fumarate;4H-Thieno(3,2-b)(1)benzazepine-4-propanamine, N,N-dimethyl-, (E)-2-butenedioate (1:1);37967-99-0;LS-152252

Suppliers and Price of N,N-Dimethyl-4H-thieno(3,2-b)(1)benzazepine-4-propanamine (E)-2-butenedioate (1:1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N,N-Dimethyl-4H-thieno(3,2-b)(1)benzazepine-4-propanamine (E)-2-butenedioate (1:1)

Chemical Property:

Vapor Pressure:3.17E-07mmHg at 25°C
Boiling Point:418.9°Cat760mmHg
Flash Point:207.1°C
Density:g/cm³
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:400.14567842
Heavy Atom Count:28
Complexity:461

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCCN1C2=C(C=CC3=CC=CC=C31)SC=C2.C(=CC(=O)O)C(=O)O
Isomeric SMILES:CN(C)CCCN1C2=C(C=CC3=CC=CC=C31)SC=C2.C(=C/C(=O)O)\C(=O)O

Technology Process of N,N-Dimethyl-4H-thieno(3,2-b)(1)benzazepine-4-propanamine (E)-2-butenedioate (1:1)

There total 9 articles about N,N-Dimethyl-4H-thieno(3,2-b)(1)benzazepine-4-propanamine (E)-2-butenedioate (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22751-23-1
(2-nitrophenyl)acetyl chloride

: 37967-99-0
Dimethyl-[3-(1-thia-4-aza-benzo[f]azulen-4-yl)-propyl]-amine; compound with (E)-but-2-enedioic acid

Guidance literature:: Multi-step reaction with 9 steps

1: SnCl₄ / benzene / Ambient temperature

2: p-toluenesulfonic acid / 150 °C

3: 98 percent / Zn, CH₃COOH

4: DCC, / ethyl acetate

5: 1.) K₂CO₃, Cu, 2.) alkali / 1.) mesitylene, reflux, 22 h

6: NaH / tetrahydrofuran; hexamethylphosphoric acid triamide / Heating

7: aq. HCl

8: sodium diethylaluminium hydride / toluene / 2 h / Ambient temperature

9: ethanol / Heating

With hydrogenchloride; tin(IV) chloride; copper; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; acetic acid; dicyclohexyl-carbodiimide; sodium aluminum diethyl dihydride; zinc; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; ethyl acetate; toluene; benzene;

Reference yield:

: 38078-81-8
2-[2-(3-Bromo-thiophen-2-yl)-[1,3]dioxolan-2-ylmethyl]-phenylamine

: 37967-99-0
Dimethyl-[3-(1-thia-4-aza-benzo[f]azulen-4-yl)-propyl]-amine; compound with (E)-but-2-enedioic acid

Guidance literature:: Multi-step reaction with 6 steps

1: DCC, / ethyl acetate

2: 1.) K₂CO₃, Cu, 2.) alkali / 1.) mesitylene, reflux, 22 h

3: NaH / tetrahydrofuran; hexamethylphosphoric acid triamide / Heating

4: aq. HCl

5: sodium diethylaluminium hydride / toluene / 2 h / Ambient temperature

6: ethanol / Heating

With hydrogenchloride; copper; sodium hydride; potassium carbonate; dicyclohexyl-carbodiimide; sodium aluminum diethyl dihydride; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; ethyl acetate; toluene;

Reference yield:

: 38078-79-4
1-(3-Bromo-thiophen-2-yl)-2-(2-nitro-phenyl)-ethanone

: 37967-99-0
Dimethyl-[3-(1-thia-4-aza-benzo[f]azulen-4-yl)-propyl]-amine; compound with (E)-but-2-enedioic acid

Guidance literature:: Multi-step reaction with 8 steps

1: p-toluenesulfonic acid / 150 °C

2: 98 percent / Zn, CH₃COOH

3: DCC, / ethyl acetate

4: 1.) K₂CO₃, Cu, 2.) alkali / 1.) mesitylene, reflux, 22 h

5: NaH / tetrahydrofuran; hexamethylphosphoric acid triamide / Heating

6: aq. HCl

7: sodium diethylaluminium hydride / toluene / 2 h / Ambient temperature

8: ethanol / Heating

With hydrogenchloride; copper; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; acetic acid; dicyclohexyl-carbodiimide; sodium aluminum diethyl dihydride; zinc; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; ethyl acetate; toluene;